Compound Light Microscopes

Compound Light Microscopes

Compound Light Microscopes

Compound light microscopes from Leica Microsystems meet the highest demands whatever the application – from routine laboratory work to the research of multi-dimensional dynamic processes in living cells.

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The world’s first Microhub

Mica enables microscopy access for all, removes the constraints of traditional four-color fluorescence imaging and radically simplifies workflows.

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Light Microscopes 38

Mica

Mica. Everything you need to enable discoveries, unified in one easy-to-use system. Simultaneous 4-color widefield, confocal resolution, AI supported analysis.
Multiplex Imaging Solution Cell DIVE

Cell DIVE

Multiplex imaging solution Cell DIVE offers crystal-clear whole tissue images, the visualization of 60+ biomarkers and over 350 validated antibodies.
Confocal Light Microscope STELLARIS Cryo

STELLARIS 5 Cryo

STELLARIS 5 Cryo is a confocal light microscope system that helps you to target your area of interest for cryo-electron tomography (CryoET)
Image of C2C12 cells: The cells are stained with lamin B (magenta) which indicates nuclear structure, Hoechst (blue) indicating DNA, and γH2AX (yellow) indicating damage to DNA. Cells were imaged using a THUNDER Imager 3D Live Cell with a 63X/1.4 oil immersion objective.

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Imaging solutions offered by Leica Microsystems are designed to maximize your cell biology research.

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Frequently Asked Questions Light Microscopes

Show answer What type of accessories does my light microscope come with? What will I need to purchase separately?

Leica microscopes are modular and shipped in the configuration that best fits your stated needs or application. In case your needs change later, you can always upgrade your workstation by adding available accessories.

Show answer Do you have multiple users utilizing a single microscope? Which Leica light microscope solution allows the setup of individual user preferences?

Leica Microsystems offers the free Store & Recall software (available with the LAS X software platform for industry) which allows you to customize the microscope functions, adapting them to the requirements and needs of each individual user. The software also allows you to restore all system settings saved with the acquired image.

Show answer Calibrated and comparable images are a must. Which types of light microscope would you recommend for this need?

All our encoded microscope solutions offer calibration and image comparison. Furthermore, Leica Microsystems offers the free Store & Recall software which allows you to restore all system settings saved with the acquired image.

Show answer Do I need a computer to operate a Leica compound light microscope?

No, you don’t. By installing a FLEXACAM C1 camera, you can directly save the images on an IT network server or USB medium. You can also send the images via e-mail over your network without the need for a PC.

Show answer I need to quickly document and share results with team members. What is the best solution you can recommend?

With the FLEXACAM C1 camera you can directly save images on an IT network server or USB medium. You can also send the images via e-mail without having to use a computer.

Show answer What kinds of modular accessories are available to extend the range of use of my microscope?

There are a lot of accessories. Please get in contact with your local Leica sales representative.

Show answer How are ergonomic accessories designed to reduce repetitive strain injuries during long working hours?

There are a lot of ergonomic accessories for Leica light microscopes. Please contact your local Leica sales representative for more details or visit: Ergonomic Accessories for Stereo Microscopes

Show answer Is the Leica Application Suite (LAS) X software both Windows and MAC compatible? How about Linux?

LAS X software only runs with Windows, but for a MAC we have a dedicated software called ‎Leica Acquire that you could download for free from the Apple store: https://apps.apple.com/it/app/leica-acquire/id733706983?mt=12
However, there is no software for Linux.

Show answer Are Leica microscopes only compatible with the Leica Application Suite software? Is integration with a 3rd party software possible?

Yes, use of a 3rd party software is possible: https://www.splashtop.com/classroom

Show answer Other than Leica cameras, can I mount 3rd party SLR/DSLR cameras to a Leica microscope or macroscope for that matter?

We have adapters for all C-mount compatible cameras.

Show answer Are there any mobile solutions for learning and sharing? Android or iOS?

The free AirLab software, compatible with iOS or ANDROID, allows the user to immediately share images, videos, and comments.

Show answer What is a compound light microscope?

A compound microscope uses optics to produce a magnified image of a sample so that with details of it can be observed that are undetectable with the naked eye. The most basic optics of a compound microscope has at least 2 lenses: i) an objective placed nearby the sample which creates a magnified, real image of it and ii) eyepieces or oculars which are used to view the real image of the sample. A human who looks through the eyepieces sees the sample as a virtual image on his/her retina. For more information, please refer to the Science Lab article: Optical Microscopes – Some Basics

Show answer What is the maximum magnification of a compound light microscope?

The maximum useful magnification value achieved with any type of light microscope depends on its ultimate resolving power or maximal resolution. The resolution depends on the microscope objective lens numerical aperture (NA). At low magnification values, the NA is small leading to a low resolution. At high magnification values, the NA is high yielding a high resolution. However, because the NA has a finite maximum value, approximately 1.3, the “useful” range of magnification is limited to about 1,800x for conventional light microscopes. Magnification beyond the useful range, which can occur whenever digital microscope cameras display images on large monitors, is called "empty” magnification. In this non-useful magnification range, the sample structures appear larger, but no additional details are resolved. For more information, please refer to the Science Lab articles: Beware of "Empty" Magnification, What Does 30,000:1 Magnification Really Mean?

Virology

Light microscopes help in many areas concerning the study of cellular mechanisms and immune responses for virology research. The study of virus-infected tissues and cells help improve the understanding of infection mechanisms and develop treatments against viral diseases which can have a dramatic impact on human health.

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Materials Science

Excellent sample preparation and imaging methods are key for visualizing the fine details of materials with reliability and accuracy. Leica light microscope solutions enable you to achieve this goal with high-quality optics and intelligent automation for optimal workflows and analysis.

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Semiconductor Inspection

Light microscope solutions help suppliers and device manufacturers achieve fast and precise inspection and analysis for semiconductor wafer processing. Conformity to the defined specifications during semiconductor device manufacturing is critical for reliability.

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Pharmaceutical Chemical Engineering Research

Pharmaceutical and chemical manufacturing, research and development requires microscope, camera and software solutions to help users clearly and precisely visualize, analyze, and document results while ensuring the highest level of accuracy. Improve experimental efficiency and reduce strain from repetitive tasks during production while achieving the excellent quality results needed.

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