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Newcastle University, BioImaging Unit, UK

The Bio-Imaging Unit is one of a number of facilities available for commercial use at Newcastle University.

Our equipment can accommodate fixed and live-cell requirements and is supported by several networked and dedicated workstations.

We can deliver a wide variety of imaging requirements:

  • Conventional brightfield microscopy
  • Phase Contrast / DIC microscopy
  • Widefield Fluorescence microscopy
  • Confocal-microscopy including two-photon microscopy 
  • High-content widefiled screening and Slidescanning

This allows us to cover a wide range of imaging techniques:

  • Fluorescence Recovery After Photobleach (FRAP)
  • Forster Resonance Energy Transfer (FRET)
  • time lapse (live-cell)
  • volume (z-stack) imaging

Source: (11/27/2023)

DNA Replication in Cancer Cells

DNA synthesis can be impeded by collisions between the DNA replication machinery and co-transcriptional R-loops leading to a major source of genomic instability in cancer cells. In this paper we…
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