Newcastle University, BioImaging Unit, UK
The Bio-Imaging Unit is one of a number of facilities available for commercial use at Newcastle University.
Our equipment can accommodate fixed and live-cell requirements and is supported by several networked and dedicated workstations.
We can deliver a wide variety of imaging requirements:
- Conventional brightfield microscopy
- Phase Contrast / DIC microscopy
- Widefield Fluorescence microscopy
- Confocal-microscopy including two-photon microscopy
- High-content widefiled screening and Slidescanning
This allows us to cover a wide range of imaging techniques:
- Fluorescence Recovery After Photobleach (FRAP)
- Forster Resonance Energy Transfer (FRET)
- time lapse (live-cell)
- volume (z-stack) imaging
Source: https://www.ncl.ac.uk/bioimaging/ (11/27/2023)
DNA Replication in Cancer Cells
DNA synthesis can be impeded by collisions between the DNA replication machinery and co-transcriptional R-loops leading to a major source of genomic instability in cancer cells. In this paper we…