Mica Microhub
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Publications
A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS–FTD
https://doi.org/10.1038/s41591-023-02788-5
Irwin KE, Jasin P, Braunstein KE, Sinha IR, Garret MA, et al.
Nature Medicine
2024 vol: 30(2) pp:382–93
Flexible ultrasound-induced retinal stimulating piezo-arrays for biomimetic visual prostheses
https://doi.org/10.1038/s41467-022-31599-4
Jiang L, Lu G, Zeng Y, Sun Y, Kang H, et al.
Nature Communications
2022 vol: 13(1) pp:3853
Ultra-transparent, hard and antibacterial coating with pendent quaternary pyridine salt
https://doi.org/10.1016/j.porgcoat.2022.107369
Cao Y, Yang Z, Ou J, Jiang L, Chu G, et al.
Progress in Organic Coatings
2023 vol: 175 pp:107369
Living Magnetotactic Microrobots Based on Bacteria with a Surface-Displayed CRISPR/Cas12a System for Penaeus Viruses Detection
https://doi.org/10.1021/acsami.3c09690
Chen H, Zhou T, Li S, Feng J, Li W, et al.
ACS Applied Materials & Interfaces
2023
Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT
https://doi.org/10.1038/s41467-023-36122-x
Paul I, Bolzan D, Youssef A, Gagnon KA, Hook H, et al.
Nature Communications
2023 vol: 14(1) pp:688
TMEM135 maintains the equilibrium of osteogenesis and adipogenesis by regulating mitochondrial dynamics
https://doi.org/10.1016/j.metabol.2023.155767
Liu J, Bao X, Huang J, Chen R, Tan Y, et al.
Metabolism
2024 vol: 152 pp:155767
Twin-bioengine self-adaptive micro/nanorobots using enzyme actuation and macrophage relay for gastrointestinal inflammation therapy
https://doi.org/10.1126/sciadv.adc8978
Zhang B, Pan H, Chen Z, Yin T, Zheng M, et al.
Science Advances
2023 vol: 9(8) pp:eadc8978
KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions and their impairment causes aplasia cutis
https://doi.org/10.1172/JCI174138
Raymundo JR, Zhang H, Smaldone G, Zhu W, Daly KE, et al.
The Journal of Clinical Investigation
2023
Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids
https://doi.org/10.3390/biomedicines12010087
Romanzi A, Milosa F, Marcelli G, Critelli RM, Lasagni S, et al.
Biomedicines
2024 vol: 12(1) pp:87
Endometrial organoids: a reservoir of functional mitochondria for uterine repair
https://doi.org/10.7150/thno.90538
Hwang S-Y, Lee D, Lee G, Ahn J, Lee Y-G, et al.
Theranostics
2024 vol: 14(3) pp:954–72
Interview with Prof. Kang (last author)
Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway
https://doi.org/10.1016/j.lfs.2024.122555
Xu X, Zhu M, Zu Y, Wang G, Li X, et al.
Life Sciences
2024 vol: 343 pp:122555
Scaffold-free three-dimensional cartilage regeneration based on cartilaginous organoids bioassembly technology
https://doi.org/10.1002/agt2.619
Huo Y, Ci Z, Wu S, Feng S, Sun Y, et al.
Aggregate
2024 pp:e619
Dendrimer Platforms for Targeted Doxorubicin Delivery—Physicochemical Properties in Context of Biological Responses
https://doi.org/10.3390/ijms25137201
Szota M, Szwedowicz U, Rembialkowska N, Janicka-Klos A, Doveiko D, et al.
International Journal of Molecular Sciences
2024 vol: 25(13) pp:7201
Optimized rAAV8 targeting acinar KLF4 ameliorates fibrosis in chronic pancreatitis via exosomes-enriched let-7s suppressing pancreatic stellate cells activation
https://doi.org/10.1016/j.ymthe.2024.06.030
Zhao Y, Feng Y, Sun F, Li L, Chen J, et al.
Molecular Therapy
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Popular Configurations
Mica 20x LWD Objective with Service Installation20x long working distance objective for imaging on glass and plastic bottom carriers. To penetrate deeper into samples using everyday standard plastic-bottom multi well plates, this Long Working Distance (LWD) objective has been optimized for use with Mica. · No need to sacrifice image quality · No need for costly glass-bottom alternatives · Avoid the frustration of switching carriers and re-optimizing your sample preparation protocols Why is long working distance important? · Focus deeper, capturing clearer images even with thicker or non-adherent samples such as organoids, spheroids and zebrafish larvae · Get increased compatibility with high-skirt well plates · Improve access to outer wells of multi well plates Please note: This objective requires service installation to ensure correct installation and calibration. A half-day service visit by our expert team is added to ensure optimal performance and system compatibility.
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Mica Widefield Live Cell Microhub Automated MicroscopeSimplify advanced live cell and fluorescence imaging. Get reliable, expert level microscopy results faster with extensive intelligent automation, AI-supported analysis, and an interface designed for ease of use. Perform long-term live cell experiments up to 4x faster than traditional widefield systems, capturing events that may previously have been missed. Easily get quality images as Mica automatically corrects the focus during experiments. Minimise phototoxicity and maintain optimal cell health with full environmental control. Ideal for long-term live-cell studies at near physiological conditions. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS: Get true simultaneous capture of up to four labels without spatiotemporal mismatch – at near-physiological conditions for live cells, or with fixed samples. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
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Mica Widefield Microhub Automated MicroscopeSimplify advanced fluorescence imaging through extensive intelligent automation, AI‑supported analysis, and an easy-to-use interface. Now all lab members can get expert microscopy results, regardless of experience. Ideal for exploration and high-throughput fluorescence imaging of fixed samples. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS: Get true simultaneous capture of up to four labels for fast acquisitions. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
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Mica WideFocal Live Cell Microhub Automated MicroscopeCombine widefield and confocal imaging in an incubating environment and simplify advanced live cell and fluorescence imaging. Extensive intelligent automation, AI-supported analysis, and an easy-to-use interface help you achieve expert microscopy results without all the training. Perform long-term live cell experiments up to 4x faster than traditional widefield systems, capturing events that may previously have been missed. Easily get quality images as Mica automatically corrects the focus during experiments. Minimise phototoxicity and maintain optimal cell health with full environmental control. Ideal for long-term and dynamic live cell studies of organoids, spheroids, and 3D cultures. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS: Visualize in widefield and switch effortlessly to confocal without ever moving your sample. Get true simultaneous capture of up to four labels without spatiotemporal mismatch – at near-physiological conditions for live cells, or with fixed samples. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
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Mica WideFocal Microhub Automated MicroscopeCombine widefield and confocal imaging in an easy-to-use platform and simplify advanced fluorescence imaging. By streamlining workflows and reducing complexity through intelligent automation, AI-supported analysis, you can get expert microscopy results without all the training. Ideal for high-resolution imaging of thick or complex samples. MICA BENEFITS: ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries. NO CONSTRAINTS : Visualize in widefield and switch effortlessly to confocal without ever moving your sample. Get true simultaneous capture of up to four labels for fast acquisitions. RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
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