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メディカル

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脳神経外科、眼科、形成外科、耳鼻咽喉科、歯科の専門医向けに厳選された、最新の科学・臨床リソースを探索しませんか? 貴重な症例や洞察、シンポジウムなど、多彩なコンテンツをご覧いただけます。 手術用顕微鏡の最先端技術に焦点を当て、AR蛍光、3D視覚化、術中OCTイメージングといった革新的技術が、複雑な手術の精度向上や意思決定の最適化にどのように貢献するかをご紹介します。
Colon adenocarcinoma and normal colon at the tumor margin. 13 biomarkers shown including Cadherin, CD3, CD4, CD8, CD20, CD31, CD45, Collagen, Caspase 9, BCL2, Beta-Catenin, Vimentin, and Smooth Muscle Actin.

Uncover the Hidden Complexity of Colon Cancer with Big Data

Colorectal cancer poses a significant health burden. While surgery is effective initially, some patients develop recurrent secondary disease with poor prognosis, necessitating advanced therapies like…
Digital microscopy simplifies documenting cell-culture results electronically while following 21 CFR part 11 guidelines for biopharma.

Introduction to 21 CFR Part 11 for Electronic Records of Cell Culture

This article provides an introduction to the recommendations of 21 CFR Part 11 from the FDA, specifically focusing on the audit trail and user management in the context of cell-culture laboratories.…
Cell DIVE multiplexed image of FFPE tissue section from syngeneic murine cancer model, 4T1.

Mapping Tumor Immune Landscape with AI-Powered Spatial Proteomics

Spatial mapping of untreated tumors provides an overview of the tumor immune architecture, useful for understanding therapeutic responses. Immunocompetent murine models are essential for identifying…
Automated Laser Microdissection for Proteome Analysis

Deep Visual Proteomics Provides Precise Spatial Proteomic Information

Despite the availability of imaging methods and mass spectroscopy for spatial proteomics, a key challenge that remains is correlating images with single-cell resolution to protein-abundance…
Multiplexed Cell DIVE imaging of Adult Human Alzheimer’s brain tissue section demonstrating expression of markers specific to astrocytes (GFAP, S100B), microglia (TMEM119, IBA1), AD-associated markers (p-Tau217, β-amyloid) and immune cells such as CD11b+, CD163+, CD4+, and HLA-DRA+, clustered around the β-amyloid plaques.

Spatial Analysis of Neuroimmune Interactions in Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neurofibrillary tangles, β-amyloid plaques, and neuroinflammation. These dysfunctions trigger or are exacerbated by…
Leitz Laborlux: Tartaric acids, polarization contrast

The Polarization Microscopy Principle

Polarization microscopy is routinely used in the material and earth sciences to identify materials and minerals on the basis of their characteristic refractive properties and colors. In biology,…
Pancreatic Ductal Adenocarcinoma imaged with Cell DIVE. Analysis done by Aivia.

A Guide to Spatial Biology

What is spatial biology, and how can researchers leverage its tools to meet the growing demands of biological questions in the post-omics era? This article provides a brief overview of spatial biology…
Image of a 12-μm thick brain section, which was stained with Toluidin blue, before dissection. It was taken with a microscope using a 63x objective.

An Introduction to Laser Microdissection

The heterogeneity of histological and biological specimens often requires isolation of specific single cells or cell groups from surrounding tissue before molecular biology analysis can be carried…
THUNDER Imager Cell を使用して実施されたストライプアッセイ。オックスフォード大学のマリア・カラスクエロ・オルダス氏より提供

神経細胞移動の分子的秘密を解き明かす

発達中の脳における特定部位への神経細胞の移動を調べるには、さまざまなアプローチを用いることができます。このウェビナーでは、オックスフォード大学の専門家が、神経発達過程における大脳皮質の機能層への神経細胞移動の分子メカニズムを解明するために使用している顕微鏡ツールとアッセイについて紹介します。これらのプロセスを理解することは、健全な脳の発達の理解を深め、神経発達障害の治療法を改善する可能性につながり…
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