Leica LMD Systems Laser Microdissection Microscopes

Dissection Perfection

Leica LMD7 Flagship

The flagship of the Leica widefield portfolio: The Leica LMD7 with scanning stage and Leica DFC7000 T camera on top port and Leica DFC3000 G camera on the side port.

Leica LMD7

Leica LMD7 with scanning stage and DFC7000 T camera on top port and DFC3000 G camera on the side port with a 22’’ pen screen and Leica LMD application software.

Leica LMD6

Leica LMD6 with motorized stage and CC7000 camera. Stage and camera can be used for the LMD7 as well.

Laser Microdissection for Spatial Proteomics

Workflow from sample preparation and imaging to downstream analysis for proteomics, incl. definition of region of interest with the help of AI.

Laser Microdissection – Autofocus before Cut

The “Autofocus before Cut” function finds a focus of the sample before each dissection process. Intended for high ROI numbers which shall be dissected successively.

Laser Microdissection – Inspect all Collectors

The „Inspect all Collectors“ tool inspects and documents all collection devices which were used for Laser Microdissection – automatically by a single mouse click.

Live cutting with the Move and Cut mode of Leica Laser Microdissection systems

(objective: 40x; contrast: brightfield (BF); specimen: mouse brain, red stain, PET steel frame) 

Leica LMD Shadow Cuts – the fastest way of laser microdissection ever!

(objective: 5x; contrast: brightfield (BF); specimen: human, H&E stained, 4 µm PEN steel frame slide)

Chromosome Dissection Training at the CENA, Brasil

This short video shows a new LMD user who practices how to dissect chromosomes according the guidance of the Leica specialists.

Popular Configurations

Effective April 7, 2025, Leica Microsystems transactions will apply an adjustment tariff charge due to new U.S. tariffs on all applicable products.
EP-DIRECTOR LMD-Slides, 50 slides

EP-DIRECTOR LMD-Slides, 50 slides

Director slides for direct ablation of material with the LMD, pack of 50 slides

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FLUO FrameSlide, glass-like, 5 pcs

FLUO FrameSlide, glass-like, 5 pcs

Metal frame slides for FLUO, glass like membrane, pack of 5 slides

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pE 300 lite SB direct fit

pE 300 lite SB direct fit

pE 300 lite SB direct fit

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PEN Frame Slide(4µm),steel frames,50pcs.

PEN Frame Slide(4µm),steel frames,50pcs.

Metal frame slides with a 4 µm thick PEN membrane, pack of 50

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PEN Membrane Slide(4µm),glass,50 slides

PEN Membrane Slide(4µm),glass,50 slides

Glass slides with a 4 µm thick PEN membrane, pack of 50

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PEN MembranSlide, glass, 50 slides

PEN MembranSlide, glass, 50 slides

For laser microdissection special membranes mounted to a glass slide are used to achieve highest quality results. Glass slides covered with a membrane with high UV absorption, making them particularly suitable for cold photo ablation (vaporization), are called glass membrane slides. Applied to the upper surface of the glass slide, the membrane is cemented to the glass at its edges. Thus, a rectangular area to mount the specimen is created where air is between the membrane and the glass backbone. The membrane is specially coated to ensure optimal adhesion of the specimens. In general, glass membrane slides have versatile application potential. Careful treatment of the foils is essential to avoid damage to the membrane. The accumulation of moisture between the glass and the membrane should be avoided, as this can cause the dissectates to stick to the glass backbone.

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PEN MembranSlide, glass, RNase-free,50pc

PEN MembranSlide, glass, RNase-free,50pc

Glass slides with a 2 µm thick PEN membrane for RNA work, Rnase-free, pack of 50

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PEN MembranSlides,glass,large,4x25 pcs

PEN MembranSlides,glass,large,4x25 pcs

Large glass slides (50x76 mm) with a 2 µm thick PEN membrane, 4 packs of 25, 100 total slides

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PEN Petri Dishes 4 µm (1 pack=20 pc)

PEN Petri Dishes 4 µm (1 pack=20 pc)

Petri dishes with 4 µm thick PEN membrane bottom for cutting, pack of 20

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PEN WhiteCoat(2µm), glass, 200 pcs

PEN WhiteCoat(2µm), glass, 200 pcs

Glass slides with a 2 µm thick PEN membrane, slide has writable area on one end, pack of 200

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PET FrameSlide, steel frames, 50 slides

PET FrameSlide, steel frames, 50 slides

PET frame slide, a pack of 50 steel frames which can also be used as sample carriers. Leica Microsystems consumables are designed to deliver reliable performance across demanding research workflows. Leica LMD slides and immersion oils work together to support precision, reproducibility, and confidence in laser microdissection and high‑resolution imaging applications. Leica LMD slides are available in multiple membrane types and formats, allowing researchers to select the optimal slide for their sample, detection method, and experimental goal. This flexibility supports both routine workflows and advanced applications such as fluorescence, while demo slide kits make it easy to compare options and identify the best fit.

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PET FrameSlide,steel frames, RNase-free

PET FrameSlide,steel frames, RNase-free

Metal frame slides with a 1.4 µm thick PET membrane for RNA work, RNase-free, pack of 50

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POL FrameSlide, steel frames, 50 slides

POL FrameSlide, steel frames, 50 slides

Metal frame slides with a 0.9 µm thick POL membrane, pack of 50

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POL FrameSlide, steel, 50pc RNase-free

POL FrameSlide, steel, 50pc RNase-free

Metal frame slides with a 0.9 µm thick POL membrane for RNA work, RNase-free, pack of 50

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PPS FrameSlide (4 µm), steel frames, 50

PPS FrameSlide (4 µm), steel frames, 50

Metal frame slides with a 4 µm thick PPS membrane, pack of 50

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pre-printed LMD Frame Slides

pre-printed LMD Frame Slides

Metal frame slides with a 4 µm thick PEN membrane with markings for automated shape imports, 10 packs of 5 slides, 50 slides total

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pre-printed LMD Membrane Slides

pre-printed LMD Membrane Slides

Glass slides with a 4 µm thick PEN membrane with markings for automated shape imports, 10 packs of 5 slides, 50 slides total

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µ-Slide w. membrane, 18well,ibidi,15 pcs

µ-Slide w. membrane, 18well,ibidi,15 pcs

18-well Ibidi u-slide with 2 µm PEN membrane bottom, pack of 15

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