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Cell Signaling Technology (CST), Danvers, Massachusetts, USA

Cell Signaling Technology (CST) is a different kind of life sciences company—one founded, owned, and run by active research scientists, with the highest standards of product and service quality, technological innovation, and scientific rigor. Founded in 1999 and headquartered in Danvers, Massachusetts, USA, CST employs over 600 people worldwide. CST consistently provide fellow scientists around the globe with best-in-class products and services to fuel their quests for discovery. CST is a company of caring people driven by a devotion to facilitating good science—a company committed to doing the right thing for our Customers, our communities, and our planet.

https://www.cellsignal.com/

Adult human Alzheimer’s brain demonstrating a panel of 15 markers.

The Shape of the Brain: Spatial Biology of Alzheimer’s Disease

Uncover cell identity and brain structure in Alzheimer's disease with Cell DIVE multiplexed imaging, demonstrating how spatial biology can lead to advances in therapy development for…
Cell counts for each biomarker were divided by total number of cells to give a percentage of biomarker positive cells out of total cells for each biomarker.

Methods to Improve Reproducibility in Spatial Biology Research

Establish reproducibility results for a Cell DIVE multiplexed imaging study in cancer research using the BAB 200 automated system from ASLS and validated antibodies from CST
PDAC Multiplexed imaging of CST panels enables an examination of immune cell components in pancreatic ductal adenocarcinoma (IPDAC) tissue on a single slide.

Characterizing tumor environment to reveal insights and spatial resolution

Antibodies from Cell Signaling Technology are validated for use with the Cell DIVE multiplexing workflow and used to probe cell lineages in the tumor microenvironment
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