A Guide to Using Microscopy for Drosophila (Fruit Fly) Research
The fruit fly, typically Drosophila melanogaster, has been used as a model organism for over a century. One reason is that many disease-related genes are shared between Drosophila and humans. It is…
Development and Derisking of CRISPR Therapies for Rare Diseases
This on-demand presentation by Dr. Fyodor Urnov and Dr. Sadik Kassim, originally delivered at ASGCT 2025, focused on a critical challenge in genetic medicine: how to scale CRISPR therapies from…
Microscope Calibration for Measurements: Why and How You Should Do It
Microscope calibration ensures accurate and consistent measurements for inspection, quality control (QC), failure analysis, and research and development (R&D). Calibration steps are described in this…
Multiplexed Imaging Reveals Tumor Immune Landscape in Colon Cancer
Cancer immunotherapy benefits few due to resistance and relapse, and combinatorial therapeutic strategies that target multiple steps of the cancer-immunity cycle may improve outcomes. This study shows…
AI-Powered Hi-Plex Spatial Analysis Tools for Breast Cancer Research
Breast cancer (BC) is the leading cause of cancer-related deaths in women. Investigating the tumor microenvironment (TME) is crucial to elucidate the mechanisms of tumor progression. Systematic…
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Improving Zebrafish-Embryo Screening with Fast, High-Contrast Imaging
Discover from this article how screening of transgenic zebrafish embryos is boosted with high-speed, high-contrast imaging using the DM6 B microscope, ensuring accurate targeting for developmental…
Transforming Research with Spatial Proteomics Workflows
Spatial Proteomics, Nature Methods 2024 Method of the Year, is driving research advancements in cancer, immunology, and beyond. By combining positional data with high throughput imaging of proteins in…