ライフサイエンス

ライフサイエンス

ライフサイエンス

様々な科学分野における顕微鏡の知識、研究技術、そして実用的な応用を深めるための場です。正確な観察、画像解析、そして研究の進歩を実現する方法を学びましょう。高度な顕微鏡技術、イメージング技術、サンプル前処理、画像解析に関する専門的な知見を提供します。最先端のアプリケーションやイノベーションを中心に、細胞生物学、神経科学、がん研究などの分野を幅広くカバーしています。
U2OS cells transfected with an Mx1-GFP plasmid (signal enhanced using Alexa Fluor 488-conjugared anti-GFP antibody) and co-stained for nuclear DNA (Hoechst 33342), microtubules (Alexa 555) and F-actin (ATTO 643). Image was captured on Mateo FL.

Microscopy and AI Solutions for 2D Cell Culture

This eBook explores the integration of microscopy and AI technologies in 2D cell culture workflows. It highlights how traditional imaging methods—such as brightfield, phase contrast, and…
Cell DIVE multiplexed image of FFPE tissue section from human invasive ductal carcinoma (IDC)

AI-Powered Hi-Plex Spatial Analysis Tools for Breast Cancer Research

Breast cancer (BC) is the leading cause of cancer-related deaths in women. Investigating the tumor microenvironment (TME) is crucial to elucidate the mechanisms of tumor progression. Systematic…
Final Segmentation of organelles in Trichomonas species. Magenta – costa, light blue – hydrogenosomes, turquoise – ER, red – vacuoles, yellow – axostyle, green – Golgi apparatus. Sample courtesy of Isabelle Guerin-Bonne, Low Kay En, Electron Microscopy Unit, Yong Loo Lin School of Medicine, National University of Singapore. Scale bar: 1 µm.

Volume EM and AI Image Analysis

The article outlines a detailed workflow for studying biological tissues in three dimensions using volume-scanning electron microscopy (volume-SEM) combined with AI-assisted image analysis. The focus…

How a Breakthrough in Spatial Proteomics Saved Lives

Toxic epidermal necrolysis (TEN) is a rare but devastating reaction to common medications like antibiotics or gout treatments. It begins innocuously, often as a rash, but can escalate rapidly into…
Some 2D measurements, e.g., lengths and areas, made on a PCB sample with a Leica measurement microscope using the Enersight software.

How to Select the Right Measurement Microscope

With a measurement microscope, users can measure the size and dimensions of sample features in both 2D and 3D, something crucial for inspection, QC, failure analysis, and R&D. However, choosing the…
These images illustrate the need for multiple z-slices to capture all gH2Ax foci in a given cell and get an accurate count.

Development and Derisking of CRISPR Therapies for Rare Diseases

This on-demand presentation by Dr. Fyodor Urnov and Dr. Sadik Kassim, originally delivered at ASGCT 2025, focused on a critical challenge in genetic medicine: how to scale CRISPR therapies from…
Example of calibrating a microscope at a higher magnification value using a stage micrometer.

Microscope Calibration for Measurements: Why and How You Should Do It

Microscope calibration ensures accurate and consistent measurements for inspection, quality control (QC), failure analysis, and research and development (R&D). Calibration steps are described in this…

Integrated Serial Sectioning and Cryo-EM Workflows for 3D Biological Imaging

This on-demand webinar explores how integrated tools can support electron microscopy workflows from sample preparation to image analysis. Experts Andreia Pinto, Adrian Boey, and Hoyin Lai present the…
Cell DIVE multiplexed image of FFPE tissue section from human colon adenocarcinoma tissue.

Multiplexed Imaging Reveals Tumor Immune Landscape in Colon Cancer

Cancer immunotherapy benefits few due to resistance and relapse, and combinatorial therapeutic strategies that target multiple steps of the cancer-immunity cycle may improve outcomes. This study shows…
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