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Sample Preparation for Electron Microscopy
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EM GP2 Automatic Plunge Freezer
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High-Pressure Freezing for Organoids: Cryo CLEM & FIB Lift Out
Master cryo EM workflow steps for challenging 3D samples: when to choose HPF vs. plunge freezing, reproducible blotting/ice control, contamination aware transfers, Cryo CLEM 3D targeting in organoids,…
From Bench to Beam: A Complete Correlative Cryo Light Microscopy Workflow
In the webinar entitled "A Multimodal Vitreous Crusade, a Cryo Correlative Workflow from Bench to Beam" a team of experts discusses the exciting world of correlative workflows for structural biology…
A Guide to Cryo-Electron Tomography
Cryo-electron tomography (CryoET) is used to resolve biomolecules within their cellular environment down to an unprecedented resolution below one nanometer.
Workflows and Instrumentation for Cryo-electron Microscopy
Cryo-electron microscopy is an increasingly popular modality to study the structures of macromolecular complexes and has enabled numerous new insights in cell biology. In recent years, cryo-electron…
A Practical Guide to Virology Research
Leica solutions for imaging and sample preparation help you with the investigation of viral entry and fusion, genome integration, viral replication, assembly, and virus budding.
Improve Cryo Electron Tomography Workflow
Leica Microsystems and Thermo Fisher Scientific have collaborated to create a fully integrated cryo-tomography workflow that responds to these research needs: Reveal cellular mechanisms at…
Expert Knowledge on High Pressure Freezing and Freeze Fracturing in the Cryo SEM Workflow
Get an insight in the working methods of the laboratory and learn about the advantages of Cryo SEM investigation in EM Sample Preparation. Find out how high pressure freezing, freeze fracturing and…
Immersion Freezing for Cryo-Transmission Electron Microscopy: Applications
A well established usage case for cryo-TEM is three-dimensional reconstruction of isolated macromolecules, virus particles, or filaments. These approaches are based on averaging of repetitive…
EM Sample Prep Workflows & Uses
Researchers can consistently achieve high-quality, precise, and reproducible results when imaging samples with electron microscopy by using Leica sample preparation solutions. Our solutions support…
Fields of Application
EM Sample Prep Workflows & Uses
Researchers can consistently achieve high-quality, precise, and reproducible results when imaging samples with electron microscopy by using Leica sample preparation solutions. Our solutions support…
