Science Lab

Bem-vindo ao portal de conhecimento da Leica Microsystems. Você encontrará pesquisas científicas e material didático sobre o tema microscopia. O portal oferece suporte a iniciantes, profissionais experientes e cientistas em seus trabalhos e experimentos diários. Explore tutoriais interativos e notas de aplicação, descubra os fundamentos da microscopia, bem como as tecnologias de ponta. Faça parte da comunidade do Science Lab e compartilhe sua experiência.

Blood vessel system of a zebrafish larvae

Overcoming Challenges with Microscopy when Imaging Moving Zebrafish Larvae

Zebrafish is a valuable model organism with many beneficial traits. However, imaging a full organism poses challenges as it is not stationary. Here, this case study shows how zebrafish larvae can be…

GLOW800 Augmented Reality Fluorescence used for real-time blood flow visualization in aneurysm clipping surgery

Aneurysm Clipping: Assessing Perforators in Real-Time with AR Fluorescence

This article covers two aneurysm clipping cases highlighting the clinical benefits of GLOW800 Augmented Reality Fluorescence application in neurosurgery, based on insights from Prof. Tohru Mizutani,…

GLOW400 AR Fluorescence in anatomy view, image courtesy of Prof. Kondo

How to Achieve Brain Tissue Resection with GLOW400 AR

Intraoperative MRI is one form of real-time intraoperative visualization, but if more in-depth visualization to identify a tumor during surgery is wanted, intraoperative fluorescence diagnostics is…

Exploring Microbial Worlds: Spatial Interactions in 3D Food Matrices

The Micalis Institute is a joint research unit in collaboration with INRAE, AgroParisTech, and Université Paris-Saclay. Its mission is to develop innovative research in the field of food microbiology…

Immunofluorescence image of a mouse enodmetrial organoid stained with CK14 and DAPI

Advancing Uterine Regenerative Therapies with Endometrial Organoids

Prof. Kang's group investigates important factors that determine the uterine microenvironment in which embryo insertion and pregnancy are successfully maintained. They are working to develop new…

Dapi – Nucleus, GFP – Plasma Membrane, Thickness 100µm, 63x objektive, 469 Z planes, 2 channels, THUNDER Imager 3D Cell Culture. Courtesy M.Sc. Dana Krauß, Medical University of Vienna (Austria).

How Efficient is your 3D Organoid Imaging and Analysis Workflow?

Organoid models have transformed life science research but optimizing image analysis protocols remains a key challenge. This webinar explores a streamlined workflow for organoid research, starting…

AI-based transfection analysis (left) of U2OS cells which were transfected with a fluorescently labelled protein. A fluorescence image of the cells (right) is also shown. The analysis and imaging were performed with Mateo FL.

Leveraging AI for Efficient Analysis of Cell Transfection

This article explores the pivotal role of artificial intelligence (AI) in optimizing transfection efficiency measurements within the context of 2D cell culture studies. Precise and reliable…

AI-based cell counting performed with a phase-contrast and fluorescence image using the Mateo FL microscope.

Precision and Efficiency with AI-Enhanced Cell Counting

This article describes the use of artificial intelligence (AI) for precise and efficient cell counting. Accurate cell counting is important for research with 2D cell cultures, e.g., cellular dynamics,…

Image of confluent cells taken with phase contrast (left) and analyzed for confluency using AI (right).

AI Confluency Analysis for Enhanced Precision in 2D Cell Culture

This article explains how efficient, precise confluency assessment of 2D cell culture can be done with artificial intelligence (AI). Assessing confluency, the percentage of surface area covered,…