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Optische Kohärenztomographie (OCT)

Systeme für optische Kohärenztomographie (OCT) von Leica unterstützen Augenärzte, Augenchirurgen und Forscher mit bedienerfreundlicher, hochwertiger Bildgebungstechnologie. Präklinische OCT-Lösungen werden bei der Erforschung von Augenerkrankungen eingesetzt, während klinische OCT-Systeme helfen, den pathologischen Zustand zu diagnostizieren. Die Systeme erleichtern das Erkennen und Überwachen morphologischer Veränderungen des Augengewebes und arbeiten nicht-invasiv und berührungsfrei.

OCT von Leica Microsystems

Nach der Übernahme von Bioptigen im Jahr 2015 bietet Leica OCT-Bildgebungssysteme für die klinische Ophthalmologie und präklinische Forschung an.

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Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen.

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Image of an onion flake taken with a basic Leica compound microscope after it was tested for resistance to fungus and mold growth following part 11 of the ISO 9022 standard.

ISO 9022 Standard Part 11 - Testing Microscopes with Severe Conditions

This article describes a test to determine the robustness of Leica microscopes to mold and fungus growth. The test follows the specifications of the ISO 9022 part 11 standard for optical instruments.

Immersion Objectives

How an immersion objective, which has a liquid medium between it and the specimen being observed, helps increase the numerical aperture and microscope resolution is explained in this article.
Intensity distribution (arbitrary color coding) of an image of two points where the distance between them corresponds to the Rayleigh criterion.

Microscope Resolution: Concepts, Factors and Calculation

This article explains in simple terms microscope resolution concepts, like the Airy disc, Abbe diffraction limit, Rayleigh criterion, and full width half max (FWHM). It also discusses the history.

Factors to Consider When Selecting a Research Microscope

An optical microscope is often one of the central devices in a life-science research lab. It can be used for various applications which shed light on many scientific questions. Thereby the…
Spherical aberration describes the fact that waves which pass through the centre of the lens are refracted less than the waves which pass through the edges of the curved lens.

Eyepieces, Objectives and Optical Aberrations

For most microscope applications, there are generally only two sets of optics which are adjusted by the user, namely, the objectives and the eyepieces. Of course, this is assuming that the microscope…
Steps of Koehler Illumination

Koehler Illumination: A Brief History and a Practical Set Up in Five Easy Steps

The technique of Koehler Illumination is one of the most important and fundamental techniques in achieving optimum imaging in any given light microscope set-up. Although it should be routinely used as…
Angular aperture

Collecting Light: The Importance of Numerical Aperture in Microscopy

Numerical aperture (abbreviated as ‘NA’) is an important consideration when trying to distinguish detail in a specimen viewed down the microscope. NA is a number without units and is related to the…

Optimization of the Interplay of Optical Components for Aberration Free Microscopy

Optical microscopes are used to magnify objects which are otherwise invisible for the human eye. For this purpose high quality optics is necessary to achieve appropriate resolution. However, besides…
Infinity port

Infinity Optical Systems

“Infinity Optics” refers to the concept of a beam path with parallel rays between the objective and the tube lens of a microscope. Flat optical components can be brought into this “Infinity Space”…
A 17th-century compound microscope (© Golub Collection – University of California, Berkeley/Steven Ruzin, Curator)

A Brief History of Light Microscopy

The history of microscopy begins in the Middle Ages. As far back as the 11th century, plano-convex lenses made of polished beryl were used in the Arab world as reading stones to magnify manuscripts.…
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