Science Lab

Bem-vindo ao portal de conhecimento da Leica Microsystems. Você encontrará pesquisas científicas e material didático sobre o tema microscopia. O portal oferece suporte a iniciantes, profissionais experientes e cientistas em seus trabalhos e experimentos diários. Explore tutoriais interativos e notas de aplicação, descubra os fundamentos da microscopia, bem como as tecnologias de ponta. Faça parte da comunidade do Science Lab e compartilhe sua experiência.

Visualizing Life in 3D at High Speed with Viventis SCAPE

Discover how oblique plane microscopy (OPM) enables light sheet imaging through a single objective, combining illumination and detection in a geometry that is compatible with conventional sample…

Single-plane image acquired 200 μm deep inside a cleared mouse gastruloid

Volumetric Imaging of Cleared Organoids with Light Sheet

Cleared organoid imaging with Viventis Deep light sheet: rapid, high-resolution imaging of large organoids throughout their full volume.

Fixed patient-derived neuroendocrine tumor organoids labeled with DAPI (cyan) and phalloidin (magenta), imaged using Viventis SCAPE; scale bar 50μm. Courtesy of Marina Cuenca and Heleen Jungen (Dayton lab), EMBL Barcelona.

What’s the Best Organoid Imaging Approach for Early Drug Discovery?

Organoids and other complex in vitro models (CIVMs) are becoming increasingly important in early drug discovery and translational research, driven by the need for more predictive, human-relevant data…