Optical Coherence Tomography (OCT)

Leica Optical Coherence Tomography (OCT) systems support ophthalmologists, ophthalmic surgeons, and researchers with easy-to-use, high-quality imaging technology.

The preclinical OCT solutions provide insight into eye disease research, while the clinical OCT systems serve as an aid in diagnosing pathological conditions. Each system is non-invasive, contact-free, and helps detect and monitor morphological changes of ocular tissue.

OCT from Leica Microsystems

With the acquisition of Bioptigen in 2015, Leica Microsystems offers OCT imaging systems for clinical ophthalmology and preclinical research.

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EnFocus intraoperative OCT, built into the Proveo 8 ophthalmic microscope gives surgeons greater insights, immediate confirmation, and maximum freedom in the OR. Get an immediate visual confirmation of how sub-surface tissue reacts to surgical maneuvers in crisp high-resolution OCT imaging. 

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Envisu clinical OCTOCT has become a standard in the clinic, the Envisu is our noninvasive, non-contact handheld solution that aids in diagnosis and monitoring of pediatric retinal disease from neonatal infants to adults.

OCT Imaging

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OCT Imaging System Envisu C-Class

Envisu C-Class

Optical Coherence Tomography for Ophthalmology

Visualization for Ophthalmic Surgeons

Perioperative OCT provides anatomic feedback to the surgeon, which aids in the visualization of physiological and pathological conditions during ophthalmic surgery, and helps guide surgical decision making in anterior as well as posterior cases.

Our product solution: EnFocus

Insight for Researchers

Research OCT imaging systems support small to large animal eye research through high-quality, rapid, and contact-free image acquisition.

Our product solution: Envisu R-Class

Diagnostic Support for Ophthalmologists

Bioptigen’s OCT systems have revolutionized the clinical practice of ophthalmology by providing high-resolution images, ultra-fast scanning, and deep insight into anatomic information. It has become the gold standard imaging modality for many conditions for aiding in the diagnosis and monitoring of therapeutic outcomes, and has quickly become one of the most frequently ordered diagnostic tests in all of medicine. Envisu, is a hand-held OCT solution with an intended use to aid in the diagnosis of physiological and pathologic conditions of the eye.

Our product solution: Envisu C-Class

About Optical Coherence Tomography (OCT)

Optical coherence tomography (OCT) is an imaging technology with applications in biology, medicine, and materials investigations. In a clinical environment, OCT has revolutionized the clinical practice of ophthalmology by providing 3D anatomic information. In preclinical research, OCT facilitates early stage research into pathology and drug discovery. This non-invasive technique is used to detect and monitor morphological changes of ocular tissue, in particular retinal layer thickness, which may aid in the diagnosis of certain pathological conditions such as glaucoma, age-related macular degeneration (AMD) or diabetic retinopathy. In this Sciecne Lab topic you can find basic information about OCT, articles with application examples, case studies, and links to selected publications.

Related Articles

Read our latest articles about Optical Coherence Tomography

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments.

More Articles

Intraoperative OCT as a Tool to Treat Diabetic Patients

In this interview, Asheesh Tewari, MD, details his experience with Proveo 8 with EnFocus Intraoperative OCT from Leica Microsystems. He finds it a powerful tool in treating his diabetic patients.…
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Clinical Symposium on OCT-guided Cornea Surgery

In this recording Prof. Mehta from Singapore National Eye Centre and Prof. Fontana from Santa Maria Nuova Hospital in Regio Emilia, Italy, share their expertise on corneal surgery. They present PK,…
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Towards Advanced Use of Intraoperative OCT in Cataract Surgery

In this White Paper, Dr. Rachid Tahiri shares his personal experience with the Leica EnFocus intraoperative OCT, the valuable features supporting smooth surgery and how it allows him to minimize…
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Residual Fragment Assessment with the Proveo 8 Intraoperative OCT

In the brief video presented below, Dr. Rachid Tahiri, an ophthalmic surgeon at the Centre d’Ophtalmologie in Granville, France shares his experience in using Proveo 8 intraoperative OCT in cataract…
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Cataract Incision Analysis Using EnFocus Intraoperative OCT

Ophthalmic surgery requires high levels of accuracy and precision for optimal surgical maneuvers and tissue manipulation. Surgical microscopes play an essential role in helping ophthalmic surgeons…
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Intraoperative OCT-Assisted Surgical Management of Proliferative Vitreoretinopathy

Proliferative vitreoretinopathy (PVR) is a plague to patients and their surgeons after recent rhegmatogenous retinal detachment (RD). Despite excellent initial surgical outcomes, it is the most common…
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Moving to Routine Use of Intraoperative OCT in Eye Surgery

Dr Barbara Parolini is one of the pioneers in the use of intraoperative OCT in eye surgery. Since 2016, she has gained a lot of clinical experience with different intraoperative OCT systems. In this…
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How OCT-guided eye surgery can help you to Focus on Perfection

Watch the successful clinical online symposium on-demand. Find out what Dr. Parolini says about the benefits of OCT-guided ophthalmic surgery. She presents clinical cases and shares her experience…
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Better Decision Making during Anterior Segment Surgery

Anterior segment surgery ranges from routine cataract surgery to more complex procedures such as Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), Deep Anterior Lamellar Keratoplasty…
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Intraoperative OCT-Assisted Gene Therapy

Gene augmentation therapy is a method of ocular gene transfer for autosomal recessive or X-linked retinal dystrophies when there is insufficient functional protein manifesting as genetic disease.…
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Hand-Held OCT Clinical & Research Applications

Hand-held Optical Coherence Tomography (OCT) has revolutionized pediatric ophthalmology and has had a significant impact on ophthalmology in general. The Leica Envisu C2300 hand-held OCT allows to…
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Cornea Webinar Series: DMEK, DSAEK, and DALK cases

Exclusive 2-part webinar series by Dr. Jod S Mehta, distinguished Professor, Duke-NUS, Singapore National Eye Center. Learn DMEK, complicated DSAEK, DALK surgery, indications, techniques, and the…
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OCT-Analysis of a Clear Corneal Incision

The aim of this prospective study was to analyse the effect of lateral stromal hydration on the morphology of clear corneal incision architecture using the microscope integrated anterior segment OCT.
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What is intraoperative OCT telling us?

In the following videos are excerpts taken from a webinar delivered by Dr. Barbara Parolini. During the webinar Dr. Parolini discusses and illustrates how intraoperative OCT provides real-time,…
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Use of EnFocus Intraoperative OCT to overcome difficulties in visualization during Synechiolysis

The aim of this study was to describe intraoperative optical coherence tomography (OCT) as an adjunctive device for peripheral synechiolysis in a post-penetrating keratoplasty patient.
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Microscope-Integrated OCT Feasibility and Utility With the EnFocus System in the DISCOVER Study

This article published in the journal OSLI Retina discusses the findings of the latest phase of the DISCOVER study relating specifically to the EnFocus instrasurgical OCT system from Leica. One of the…
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How Intrasurgical OCT can Impact the Surgical Approach to Membrane Peeling

How Intrasurgical OCT can Impact the Surgical Approach to Membrane Peeling

When treating patients with vitreomacular traction (VMT), peeling of the inner limiting membrane (ILM) or an epiretinal membrane (ERM) is often indicated. Successful outcomes depend on precise…
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What is OCT and how can it help ophthalmologists acquire high resolution information on ocular tissue?

Optical Coherence Tomography (OCT) is a non-invasive, non-contact imaging modality used to visualize and monitor changes to the morphology of biological tissue. OCT employs low-coherence…
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