Optical Coherence Tomography (OCT)
The preclinical OCT solutions provide insight into eye disease research, while the clinical OCT systems serve as an aid in diagnosing pathological conditions. Each system is non-invasive, contact-free, and helps detect and monitor morphological changes of ocular tissue.
OCT from Leica Microsystems
With the acquisition of Bioptigen in 2015, Leica Microsystems offers OCT imaging systems for clinical ophthalmology and preclinical research.
Contact a local specialist for expert advice on the right OCT solution for your needs and budget.
EnFocus intraoperative OCT, built into the Proveo 8 ophthalmic microscope gives surgeons greater insights, immediate confirmation, and maximum freedom in the OR. Get an immediate visual confirmation of how sub-surface tissue reacts to surgical maneuvers in crisp high-resolution OCT imaging.
Envisu clinical OCT – OCT has become a standard in the clinic, the Envisu is our noninvasive, non-contact handheld solution that aids in diagnosis and monitoring of pediatric retinal disease from neonatal infants to adults.
OCT Imaging
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EnFocus
Intraoperative OCT imaging system
Envisu R-Class
Optical Coherence Tomography for Preclinical Researchers
Envisu C-Class
Optical Coherence Tomography for Ophthalmology
Visualization for Ophthalmic Surgeons
Perioperative OCT provides anatomic feedback to the surgeon, which aids in the visualization of physiological and pathological conditions during ophthalmic surgery, and helps guide surgical decision making in anterior as well as posterior cases.
Our product solution: EnFocus
Insight for Researchers
Research OCT imaging systems support small to large animal eye research through high-quality, rapid, and contact-free image acquisition.
Our product solution: Envisu R-Class
Diagnostic Support for Ophthalmologists
Bioptigen’s OCT systems have revolutionized the clinical practice of ophthalmology by providing high-resolution images, ultra-fast scanning, and deep insight into anatomic information. It has become the gold standard imaging modality for many conditions for aiding in the diagnosis and monitoring of therapeutic outcomes, and has quickly become one of the most frequently ordered diagnostic tests in all of medicine. Envisu, is a hand-held OCT solution with an intended use to aid in the diagnosis of physiological and pathologic conditions of the eye.
Our product solution: Envisu C-Class
About Optical Coherence Tomography (OCT)
Optical coherence tomography (OCT) is an imaging technology with applications in biology, medicine, and materials investigations. In a clinical environment, OCT has revolutionized the clinical practice of ophthalmology by providing 3D anatomic information. In preclinical research, OCT facilitates early stage research into pathology and drug discovery. This non-invasive technique is used to detect and monitor morphological changes of ocular tissue, in particular retinal layer thickness, which may aid in the diagnosis of certain pathological conditions such as glaucoma, age-related macular degeneration (AMD) or diabetic retinopathy. In this Sciecne Lab topic you can find basic information about OCT, articles with application examples, case studies, and links to selected publications.
Residual Fragment Assessment with the Proveo 8 Intraoperative OCT
In the brief video presented below, Dr. Rachid Tahiri, an ophthalmic surgeon at the Centre d’Ophtalmologie in Granville, France shares his experience in using Proveo 8 intraoperative OCT in cataract…Read article
Cataract Incision Analysis Using EnFocus Intraoperative OCT
Ophthalmic surgery requires high levels of accuracy and precision for optimal surgical maneuvers and tissue manipulation. Surgical microscopes play an essential role in helping ophthalmic surgeons…Read article
Intraoperative OCT-Assisted Surgical Management of Proliferative Vitreoretinopathy
Proliferative vitreoretinopathy (PVR) is a plague to patients and their surgeons after recent rhegmatogenous retinal detachment (RD). Despite excellent initial surgical outcomes, it is the most common…Read article
Moving to Routine Use of Intraoperative OCT in Eye Surgery
Dr Barbara Parolini is one of the pioneers in the use of intraoperative OCT in eye surgery. Since 2016, she has gained a lot of clinical experience with different intraoperative OCT systems. In this…Read article
How OCT-guided eye surgery can help you to Focus on Perfection
Watch the successful clinical online symposium on-demand. Find out what Dr. Parolini says about the benefits of OCT-guided ophthalmic surgery. She presents clinical cases and shares her experience…Read article
Better Decision Making during Anterior Segment Surgery
Anterior segment surgery ranges from routine cataract surgery to more complex procedures such as Descemet Stripping Automated Endothelial Keratoplasty (DSAEK), Deep Anterior Lamellar Keratoplasty…Read article
Intraoperative OCT-Assisted Gene Therapy
Gene augmentation therapy is a method of ocular gene transfer for autosomal recessive or X-linked retinal dystrophies when there is insufficient functional protein manifesting as genetic disease.…Read article
Hand-Held OCT Clinical & Research Applications
Hand-held Optical Coherence Tomography (OCT) has revolutionized pediatric ophthalmology and has had a significant impact on ophthalmology in general. The Leica Envisu C2300 hand-held OCT allows to…Read article
Cornea Webinar Series: DMEK, DSAEK, and DALK cases
Exclusive 2-part webinar series by Dr. Jod S Mehta, distinguished Professor, Duke-NUS, Singapore National Eye Center. Learn DMEK, complicated DSAEK, DALK surgery, indications, techniques, and the…Read article
OCT-Analysis of a Clear Corneal Incision
The aim of this prospective study was to analyse the effect of lateral stromal hydration on the morphology of clear corneal incision architecture using the microscope integrated anterior segment OCT.Read article
What is intraoperative OCT telling us?
In the following videos are excerpts taken from a webinar delivered by Dr. Barbara Parolini. During the webinar Dr. Parolini discusses and illustrates how intraoperative OCT provides real-time,…Read article
Use of EnFocus Intraoperative OCT to overcome difficulties in visualization during Synechiolysis
The aim of this study was to describe intraoperative optical coherence tomography (OCT) as an adjunctive device for peripheral synechiolysis in a post-penetrating keratoplasty patient.Read article
Microscope-Integrated OCT Feasibility and Utility With the EnFocus System in the DISCOVER Study
This article published in the journal OSLI Retina discusses the findings of the latest phase of the DISCOVER study relating specifically to the EnFocus instrasurgical OCT system from Leica. One of the…Read article
How Intrasurgical OCT can Impact the Surgical Approach to Membrane Peeling
When treating patients with vitreomacular traction (VMT), peeling of the inner limiting membrane (ILM) or an epiretinal membrane (ERM) is often indicated. Successful outcomes depend on precise…Read article
What is OCT and how can it help ophthalmologists acquire high resolution information on ocular tissue?
Optical Coherence Tomography (OCT) is a non-invasive, non-contact imaging modality used to visualize and monitor changes to the morphology of biological tissue. OCT employs low-coherence…Read article
How Intrasurgical OCT can Provide Additional Information During Ophthalmic DMEK Procedures
Replacing diseased Descemet’s membrane with a donor graft is an especially delicate procedure. Accurate positioning and full adherence to the stroma are crucial for optimal patient outcomes. These…Read article
Is iOCT the Next Paradigm Shift for Vitreoretinal Surgery?
Intraoperative ocular coherence tomography (iOCT) is a useful asset when performing macular surgery and other vitreoretinal procedures. Considering the advantages it provides, iOCT may be the next…Read article
A Healthy Dose of Interferometry
Although interferometry may once have been dismissed by the medical community because of its inability to see inside the human body, its application within the wider biomedical arena is continuing to…Read article
The Value of Intraoperative OCT Imaging in Vitreoretinal Surgery
The role of iOCT in vitreoretinal surgery continues to be defined by active research and enhancements to integrative technologies. Further research is needed to better define the specific applications…Read article
Handheld Optical Coherence Tomography During Sedation in Young Children With Optic Pathway Gliomas
Monitoring young children with optic pathway gliomas (OPGs) for visual deterioration can be difficult owing to age-related noncompliance. Optical coherence tomography (OCT) measures of retinal nerve…Read article
High Resolution Optical Coherence Tomography Guided Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty Using Reverse Big Bubble Technique
This study assessed the feasibility of High Resolution Spectral Domain Optical Coherence Tomography (HR-SDOCT) to guide donor tissue preparation in Descemet's Membrane Endothelial Keratoplasty (DMEK)…Read article
OCT Publication List
OCT is a non-invasive, contact-free technique that helps to detect and monitor morphological changes of ocular tissue, in particular retinal layer thickness, which can give insight into pathological…Read article
Intraoperative OCT Today and Tomorrow: The PIONEER Study Two-year Results and Beyond
The high-resolution, cross sectional information provided by iOCT creates a unique feedback system for vitreoretinal surgery. The PIONEER Study conducted by the Cole Eye Institute is a three-year…Read article
Video Talk by Sonia H. Yoo: Interoperative OCT Imaging of Selective Lamellar Keratoplasty
The work prepared and presented within this video demonstrates preliminary research, and the promising future of perioperative OCT to aid the diagnosis of physiological and pathological conditions…Read article
Useful Links
Ophthalmology Journals
www.scimagojr.com/journalrank.php?category=2731Journal rankings for category "Ophthalmology"
www.wjgnet.com/2218-6239/World Journal of Ophthalmology
www.aaojournal.org/Ophthalmology, the official journal of the American Academy of Ophthalmology
www.ajo.com/American journal of ophthalmology
http://bjo.bmj.com/British Journal of Ophthalmology
www.djo.harvard.edu/Digital Journal of Ophthalmology
www.springer.com/medicine/ophthalmology/journal/10792International ophthalmology
http://archopht.jamanetwork.com/journal.aspxJAMA Ophthalmology
http://journals.lww.com/internat-ophthalmology/pages/default.aspxInternational ophthalmology clinics
www.springer.com/medicine/ophthalmology/journal/10384Japanese journal of ophthalmologyhttp://www.benthamscience.com/open/toophtj/
www.benthamscience.com/open/toophtj/The open ophthalmology journal
http://journals.lww.com/co-ophthalmology/pages/default.aspxCurrent opinion in ophthalmology
http://informahealthcare.com/loi/sioSeminars in ophthalmology
www.iovs.org/Investigative ophthalmology and visual science
www.dovepress.com/clinical-ophthalmology-journalClinical ophthalmology
www.hindawi.com/journals/jop/Journal of ophthalmology
www.revophth.com/Review of ophthalmology
www.surveyophthalmol.com/Survey of ophthalmology
www.sciencedirect.com/science/journal/00084182Canadian Journal of Ophthalmology/Journal Canadien d'Ophtalmologie
www.sciencedirect.com/science/journal/13194534Saudi Journal of ophthalmology
www.healio.com/journals/jposJournal of pediatric ophthalmology and strabismus
www.elsevier.com/journals/taiwan-journal-of-ophthalmology/2211-5056Taiwan Journal of ophthalmology
www.eur-j-ophthalmol.com/European journal of ophthalmology
www.apaophth.org/eJournal/Asia-Pacific Journal of ophthalmology
www.meajo.org/Middle East African Journal of ophthalmology
www.ijo.in/Indian Journal of ophthalmology
www.ajol.info/index.php/njoAfrican Journals Online – Nigerian Journal of Opthalmology
www.canadianjournalofophthalmology.ca/Canadian Journal of Opthalmology
www.jao.medrounds.org/Journal of Academic Ophthalmology
www.ojoonline.org/Oman Journal of Ophthalmology
www.dog.org/?cat=48Graefe’s Archive for Clinical and Experimental Ophthalmology
Organizations
www.icoph.org/International council of ophthalmology
www.clinical-ophthalmology.com/The Society for Clinical Ophthalmology
www.arvo.org/The association for research in vision and ophthalmology
www.aao.org/American academy of ophthalmology – the eye M.D. association
www.esvo.org/European society of veterinary ophthalmology
www.paao.org/Pan-American Association of ophthalmology
soevision.org/European Society of Ophthalmologyhttp://www.nanosweb.org/home.cfm
www.nanosweb.org/home.cfmNorth American neuro-ophthalmology society
www.feoph-sight.eu/Federation of European ophthalmology
www.atpo.org/ATPO/Home/ATPO/Default.aspxAssociation of technical personnel in ophthalmology
www.ileyemd.org/Illinois Association of Ophthalmology
www.utaheyemds.org/Eye M.D.s of Utah
www.mdeye.org/The Florida Society of Ophthalmology
www.ophthalmicedge.org/Ophthalmic Edge
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