Science Lab

Bem-vindo ao portal de conhecimento da Leica Microsystems. Você encontrará pesquisas científicas e material didático sobre o tema microscopia. O portal oferece suporte a iniciantes, profissionais experientes e cientistas em seus trabalhos e experimentos diários. Explore tutoriais interativos e notas de aplicação, descubra os fundamentos da microscopia, bem como as tecnologias de ponta. Faça parte da comunidade do Science Lab e compartilhe sua experiência.

An Overview of Artificial Intelligence (AI) and Machine Learning

AI is rapidly changing industrial inspection, quality control, and manufacturing workflows. But not all AI technologies work the same way. From machine learning and deep learning to the newer concept…

AI-based inspection detects, classifies, and measures defects directly in microscope images of components.

AI Image Analysis for Reliable Defect Detection

AI-based visual inspection with microscopy helps make quality control in industrial environments efficient by reducing manual inspection effort concerning defect detection, classification, and…

Why the Future of Microscopic Inspection Is AI-Assisted, Not Fully Automated

The next wave of QC productivity gains will not come from building more automated inspection lines. Instead, it will come from augmenting millions of inspection decisions that are made manually every…

3D rendering of a mouse beta cell with mitochondria (blue), insulin SGs (orange), microtubules (red), nucleus (yellow), and plasma membrane (transparent).

High-Pressure Freezing Protocols for Ultrastructural 3D EM

High pressure freezing (HPF) can help preserve hydrated cells and tissues close to their biological state at the moment of immobilization, supporting more reliable ultrastructural interpretation than…

Image of glass with primary corundum having numerous inclusions. It was taken with a microscope using polarization contrast.

Ensuring Glass Quality with the Polarization Microscopy Advantage

Glass is one of the oldest materials known. Today, it is used for many applications, e.g., optical instruments, windows, doors, solar panels, containers for food, beverages, and medicine, so strict…

Mouse fibroblasts where F-actin is labelled with FITC (green), tubulin with Cy5 (red), and nuclei with DAPI (blue). Image courtesy of Dr. Günter Giese, Max Planck Institute for Medical Research, Heidelberg, Germany.

Overview of Fluorescent Dyes in terms of Applications and Properties

An introduction to commonly used fluorescent dyes and an overview of their characteristics are given in this article. Fluorescence microscopy is used for the study of specific cellular components with…

Region of a patterned wafer inspected using optical microscopy and automated and reproducible DIC (differential interference contrast). With DIC users are able to visualize small height differences on the wafer surface more easily.

6-Inch Wafer Inspection Microscope for Reliably Observing Small Height Differences

A 6-inch wafer inspection microscope with automated and reproducible DIC (differential interference contrast) imaging, no matter the skill level of users, is described in this article. Manufacturing…

A Larger 3D Area in Focus for Neurosurgical and Ophthalmic Microscopes

Neurosurgeons and ophthalmologists deal with delicate structures, deep or narrow cavities and tiny structures with vitally important functions. Seeing a clear, large 3D area of the surgical field in…

The infinite light path of a Leica microscope can be accessed between the light source and objective lens. This approach utilizing mirrors and beam splitters in the illumination path allows users to perform multiple applications with the microscope.

Infinity Optical Systems - From “Infinity Optics” to the Infinity Port

“Infinity Optics” is the concept of a light path with parallel rays between the objective and tube lens of a microscope [1]. Placing flat optical components into this “infinity space” which do not…

1 2 3 4 ... 19