Leica Microsystems

Leica Microsystems

Leica Microsystems is a world leader in microscopes and scientific instruments. Founded as a family business in the nineteenth century, the company’s history was marked by unparalleled innovation on its way to becoming a global enterprise.

Its historically close cooperation with the scientific community is the key to Leica Microsystems’ tradition of innovation, which draws on users’ ideas and creates solutions tailored to their requirements. At the global level, Leica Microsystems is organized in three divisions, all of which are among the leaders in their respective fields: Life Science, Industry and Medical.

The company is represented in over 100 countries with 6 manufacturing facilities in 5 countries, sales and service organizations in 20 countries, and an international network of dealers. The company is headquartered in Wetzlar, Germany.

http://www.leica-microsystems.com/

Confocal Optical Section Thickness

Confocal microscopes are employed to optically slice comparably thick samples.

Fluorescence microscope image of a life-science specimen

An Introduction to Fluorescence

This article gives an introduction to fluorescence and photoluminescence, which includes phosphorescence, explains the basic theory behind them, and how fluorescence is used for microscopy.

Modulation contrast visualizes transparent, low-contrast specimens.

Integrated Modulation Contrast (IMC)

Hoffman modulation contrast has established itself as a standard for the observation of unstained, low-contrast biological specimens. The integration of the modulator in the beam path of themodern…

Object planes of the Greenough stereomicroscope with depth of field range.

Depth of Field in Microscopy

In microscopy, depth of field is often seen as an empirical parameter. In practice it is determined by the correlation between numerical aperture, resolution and magnification. For the best possible…

Cochlea implant. Illustration: © MED-EL.

Cochlea Implants for Deaf and Severely Hard of Hearing

The cochlea implant (CI) replaces the function of the outer ear, the middle ear and the cochlea of the inner ear. Basically, it consists of an external unit comprising a microphone, speech processor,…

New Standard in Electrophysiology and Deep Tissue Imaging

The function of nerve and muscle cells relies on ionic currents flowing through ion channels. These ion channels play a major role in cell physiology. One way to investigate ion channels is to use…

Beware of "Empty" Magnification

This article explains how to avoid the phenomen of "empty magnification" in microscopy.

A portion of an early binocular microscope developed by John Leonhard Riddel in the early 1850s.

The History of Stereo Microscopy

This article gives an overview on the history of stereo microscopes. The development and evolution from handcrafted instruments (late 16th to mid-18th century) to mass produced ones the last 150…