Science Lab

Science Lab

Science Lab

Bienvenue sur le portail de connaissances de Leica Microsystems. Vous y trouverez des recherches scientifiques et du matériel didactique sur le thème de la microscopie. Le portail aide les débutants, les praticiens expérimentés et les scientifiques dans leur travail quotidien et leurs expériences. Explorez les didacticiels interactifs et les notes d'application, découvrez les bases de la microscopie ainsi que les technologies de pointe. Faites partie de la communauté Science Lab et partagez votre expertise.
Virally labeled neurons (red) and astrocytes (green) in a cortical spheroid derived from human induced pluripotent stem cells. THUNDER Model Organism Imager with a 2x, 0.15 NA objective at 3.4x zoom was used to produce this 425 µm Z-stack (26 positions) which is presented here as an Extended Depth of Field (EDoF) projection. Images courtesy of Dr. F. Birey, Dr. S. Pasca laboratory, Palo Alto, CA.

Guide to Live-Cell Imaging

For a wide range of applications in various research fields of life science, live-cell imaging is an indispensable tool for visualizing cells in a state as close to in vivo, i.e. living and active, as…
Mouse brain slice which was immunostained with GFAP-A647 and imaged using a THUNDER Imager Tissue. Courtesy of H. Xu, University of Pennsylvania, Philadelphia, USA.

Neurosciences

Vous souhaitez une meilleure compréhension des maladies neurodégénératives ou vous étudiez le fonctionnement du système nerveux ? Découvrez comment vous pouvez faire des percées importantes grâce aux…
3D high-plex imaging in cancer immunology. Overview of a pancreatic tumor section in mouse model, labeled with 15 markers and imaged in one go using STELLARIS with SpectraPlex. (https://www.nature.com/articles/d42473-024-00260-7)

How to Streamline High-Plex Imaging for 3D Spatial Omics Advances

In this webinar, Dr. Julia Roberti and Dr. Luis Alvarez from Leica Microsystems introduce SpectraPlex, a new functionality integrated into the STELLARIS confocal platform for high-plex 3D spatial…
Pancreatic Ductal Adenocarcinoma with 11 Apoptosis biomarkers shown – BAK, BAX, BCL2, BCLXL, Caspase9, CIAP1, NaKATPase, PCK26, SMAC, Vimentin, and XIAP.

Transforming Research with Spatial Proteomics Workflows

Spatial Proteomics, Nature Methods 2024 Method of the Year, is driving research advancements in cancer, immunology, and beyond. By combining positional data with high throughput imaging of proteins in…
Pancreatic Ductal Adenocarcinoma imaged with Cell DIVE. Analysis done by Aivia.

A Guide to Spatial Biology

What is spatial biology, and how can researchers leverage its tools to meet the growing demands of biological questions in the post-omics era? This article provides a brief overview of spatial biology…

Recherche sur le cancer

Le cancer est une maladie complexe et hétérogène causée par des cellules déficientes dans la régulation de la croissance. Les modifications génétiques et épigénétiques d’une cellule ou d’un groupe de…
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