Leica Microsystems
Leica Microsystems is a world leader in microscopes and scientific instruments. Founded as a family business in the nineteenth century, the company’s history was marked by unparalleled innovation on its way to becoming a global enterprise.
Its historically close cooperation with the scientific community is the key to Leica Microsystems’ tradition of innovation, which draws on users’ ideas and creates solutions tailored to their requirements. At the global level, Leica Microsystems is organized in three divisions, all of which are among the leaders in their respective fields: Life Science, Industry and Medical.
The company is represented in over 100 countries with 6 manufacturing facilities in 5 countries, sales and service organizations in 20 countries, and an international network of dealers. The company is headquartered in Wetzlar, Germany.
Tracking Single Cells Using Deep Learning
AI-based solutions continue to gain ground in the field of microscopy. From automated object classification to virtual staining, machine and deep learning technologies are powering scientific…
Learning the Cellular Architecture from its Optical Properties
In the last 3 years, microscopists have started to use "AI based" solutions for a wide range of applications, including image acquisition optimization (smart microscopy), object classification, image…
How to Select the Right Solution for Visual Inspection
This article helps users with the decision-making process when selecting a microscope as a solution for routine visual inspection. Important factors that should be considered are described.
How to Use a Digital Microscope to Streamline Inspection Processes
Watch this webinar for inspiration and expert advice on how to make quality control simpler, quicker, and easier. Learn how to perform comprehensive visual inspection, including comparison,…
Artificial Intelligence and Confocal Microscopy – What You Need to Know
This list of frequently asked questions provides “hands-on” answers and is a supplement to the introductory article about Dynamic Signal Enhancement powered by Aivia "How Artificial Intelligence…
How Artificial Intelligence Enhances Confocal Imaging
In this article, we show how artificial intelligence (AI) can enhance your imaging experiments. Namely, how Dynamic Signal Enhancement powered by Aivia improves image quality while capturing the…
Designing your Research Study with Multiplexed IF Imaging
Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions within a single fixed tissue sample. It is common for researchers to ask…
Mitochondrial Dynamics Quantitatively Revealed by STED Nanoscopy
Mitochondria are vital subcellular organelles, which can generate energy to support the entire lifecycle of biological cells. However, conventional fluorescence microscopy cannot provide a high enough…
Cross Section Ion Beam Milling of Battery Components
Sample Preparation of Lithium battery systems requires high quality surface preparation to evaluate their internal structure and morphology. Due to the brittle materials involved, preparing pristine…
How to Successfully Perform Live-cell CLEM
The Leica Nano workflow provides a streamlined live-cell CLEM solution for getting insight bout structural changes of cellular components over time. Besides the technical handling described in the…
How to Successfully Implement Coral Life
The live-cell CLEM workflow allows you to capture dynamic information related to a relevant biological process as it happens and put these observations into their ultrastructural context. The Leica…
Advancing Cellular Ultrastructure Research
Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the enteric glycocalyx. Freeze-fracture and etching are two…
Be Confident in your Results with Cell DIVE Validated Antibodies
The Cell DIVE System includes a carefully curated list of hundreds of commercially available antibodies validated to offer optimal specificity and sensitivity in multiplexed imaging. That validation…
Overcoming Multiplexed Imaging Roadblocks
Whether a single slide or a batch of slides processed on multiple Cell DIVE imagers, every step carried out by the Cell DIVE Acquisition Software eliminates distortions and artifacts and seamlessly…
Optimal Visualization in Brain Surgery
This case study “Treatment of the Galassi type III arachnoid cyst with the M530 OHX surgical microscope from Leica Microsystems” documents the procedure step by step and shows the visualization…
Benefits of Combining STED and Lifetime
In this interview, Professor Alberto Diaspro talks about the advantages of the White Light Laser and the TauSTED capabilities of STELLARIS 8 STED. He speaks about his experience with the confocal…
Improved Visualization of the Anterior Chamber Angle with Proveo 8
In this interview, Michael G. Richie, MD offers his expert opinion on the Proveo 8 from Leica Microsystems as a means for outstanding visualization of the anterior chamber during MIGS. He describes…
Intraoperative OCT as a Tool to Treat Diabetic Patients
In this interview, Asheesh Tewari, MD, details his experience with Proveo 8 with EnFocus Intraoperative OCT from Leica Microsystems. He finds it a powerful tool in treating his diabetic patients.…