Leica Microsystems: Science Lab

Science Lab

Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!

Spheroid stained with Cyan: Dapi nuclear countertain; Green AF488 Involucrin; Orange AF55 Phalloidin Actin; Magenta AF647 CK14.

Notable AI-based Solutions for Phenotypic Drug Screening

Learn about notable optical microscope solutions for phenotypic drug screening using 3D-cell culture, both planning and execution, from this free, on-demand webinar.

Murine esophageal organoids (DAPI, Integrin26-AF 488, SOX2-AF568) imaged with the THUNDER Imager 3D Cell Culture. Courtesy of Dr. F.T. Arroso Martins, Tamere University, Finland.

How to Get Deeper Insights into your Organoid and Spheroid Models

In this eBook, learn about key considerations for imaging 3D cultures, such as organoids and spheroids, and discover microscopy solutions to shed new insights into dynamic processes in 3D real-time

Water Flea Daphnia imaged by Electron Microscopy. Courtesy of Mag. Dr. Gruber, University of Vienna, Austria

Streamline your EM Sample Preparation Workflow for Biological Applications

Master EM sample preparation, including ultramicrotomy, for life sciences in this expert eBook!

Acrylonitrile butadiene styrene (ABS) stained with osmium tetroxide (OsO4), sectioned with a DIATOME diamond knife at room temperature, and then imaged with HAADF TEM.

Ultramicrotomy Techniques for Materials Sectioning

Learn about ultramicrotomy for materials sectioning when investigating polymers and brittle materials with transmission (TEM) or scanning electron microscopy (SEM) or atomic force microscopy.

Ausgewachsene hermaphroditische Gonaden von C. elegans, aufgenommen mit THUNDER Imager. Färbung: blau - DAPI (Zellkern), grün - SP56 (Spermien), rot - RME-2 (Eizelle), magenta - PGL-1 (RNA + Proteingranula). Bild mit freundlicher Genehmigung von Prof. Dr. Christian Eckmann, Martin-Luther-Universität, Halle, Deutschland.

Life-Science-Forschung: Welche Mikroskopkamera ist die richtige für Sie?

Wie Sie entscheiden, welche Kamera für Ihre Life-Science-Mikroskopie-Experimente die Richtige ist. Welche Kamera von Leica Microsystems ist für Sie am besten geeignet?

[Translate to German:] Stereo microscopes are often considered the workhorses of laboratories and production sites.

Wichtige Faktoren, die Sie bei der Auswahl eines Stereomikroskops berücksichtigen sollten

Stereomikroskope zeichnen sich durch ihre Fähigkeit aus, einen 3D-Eindruck der Probe zu erzeugen. Daher eignen sie sich besonders gut für Inspektion und Nacharbeit, Qualitätskontrolle, Forschung und…

Brain organoid section (DAPI) acquired using THUNDER Imager Live Cell. Image courtesy of Janina Kaspar and Irene Santisteban, Schäfer Lab, TUM.

Imaging Organoid Models to Investigate Brain Health

Imaging human brain organoid models to study the phenotypes of specialized brain cells called microglia, and the potential applications of these organoid models in health and disease.

THY1-EGFP labeled neurons in mouse brain processed using the PEGASOS 2 tissue clearing method, imaged on a Leica confocal microscope. Neurons were traced using Aivia’s 3D Neuron Analysis – FL recipe. Image credit: Hu Zhao, Chinese Institute for Brain Research.

Unlocking Insights in Complex and Dense Neuron Images Guided by AI

The latest advancement in Aivia AI image analysis software provides improved soma detection, additional flexibility in neuron tracing, 3D relational measurement including Sholl analysis and more.

What are the Challenges in Neuroscience Microscopy?

eBook outlining the visualization of the nervous system using different types of microscopy techniques and methods to address questions in neuroscience.