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Science Lab

Science Lab

Das Wissensportal von Leica Microsystems bietet Ihnen Wissens- und Lehrmaterial zu den Themen der Mikroskopie. Die Inhalte sind so konzipiert, dass sie Einsteiger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrem alltäglichen Vorgehen und Experimenten unterstützen. Entdecken Sie interaktive Tutorials und Anwendungsberichte, erfahren Sie mehr über die Grundlagen der Mikroskopie und High-End-Technologien - werden Sie Teil der Science Lab Community und teilen Sie Ihr Wissen!

Nobel Prize 2013 in Physiology or Medicine for Discoveries of the Machinery Regulating Vesicle Traffic

On October 7th 2013, The Nobel Assembly at Karolinska Institutet has decided to award The Nobel Prize in Physiology or Medicine 2012 jointly to James E. Rothman, Randy W. Schekman and Thomas C. Südhof…

Thermodynamic Considerations Regarding the LN2 in a High Pressure Freezer

Employing liquid nitrogen (LN2) as a coolant in the complex process of high pressure freezing raises certain considerations regarding phase transition not only of the liquid sample to be frozen but…

Carbon Thickness Evaluation in Electron Microscopy

The coating layers applied and used for electron microscopy imaging are commonly controlled and measured by quartz crystals. These crystals oscillate with a certain frequency (around 6 megahertz when…

Spectral Detection – How to Define the Spectral Bands that Collect Probe-specific Emission

To specifically collect emission from multiple probes, the light is first separated spatially and then passes through a device that defines a spectral band. Classically, this is a common glass-based…
Forensics microscopy

Every Clue Counts – Forensics Inconceivable Without Microscopy

There is no crime without clues. They may be obvious, like a cartridge case at the scene of the crime or clear signs of crowbar damage on a door. But sometimes, clues are microscopically small.…

Perusing Alternatives for Automated Staining of TEM Thin Sections

Contrast in transmission electron microscopy (TEM) is mainly produced by electron scattering at the specimen: Structures that strongly scatter electrons are referred to as electron dense and appear as…
QTM B, 1963, the first commercial automated image analysis system for microscope images, based on a TV camera and developed by Metals Research in Cambridge, England.

50 Years of Image Analysis

Modern image analysis systems perform highly sophisticated image processing functions on images from an automated microscope and digital camera. 50 years ago, the first image analysis system was…

Stem Cells in the Aging Process – the Signal Protein p53 as "Guardian of the Genome"

The physiological process of aging is an elementary part of life. The processes responsible for the aging process and the effect they have is one of the key focuses of biomedical research. Dr. Yvonne…
John B. Gurdon

Nobel Prize 2012 in Physiology or Medicine for Stem Cell Research

The Nobel Prize recognizes two scientists who discovered that mature, specialised cells can be reprogrammed to become immature cells capable of developing into all tissues of the body. Their findings…
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