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THUNDER Imager Live Cell & 3D Cell Culture & 3D Assay

  • Pharmaceutical Chemical Engineering Research

    Your role in pharmaceutical and chemical manufacturing, research and development requires microscope, camera and software solutions to help you clearly and precisely visualize, analyze, and document…
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  • Live Cell Imaging

    Shifting perspective from single microscope components to a full working live cell imaging solution, Leica Microsystems integrates microscope, LAS X imaging software, cameras, and dedicated…
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  • Fluorescence Microscopy

    Fluorescence is one of the most commonly used physical phenomena in biological and analytical microscopy, mainly because of its high sensitivity and high specificity. Find out how fluorescence…
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  • Zebrafish Research

    For the best result during screening, sorting, manipulation, and imaging you need to see details and structures to make the right decisions for your next steps in research. Known for outstanding…
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  • Leica photomanipulation

    Photomanipulation

    The term photomanipulation encompasses a range of techniques that utilize the properties of fluorescent molecules to initiate events and observe how dynamic complexes behave over time in living cells.…
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  • Neuroscience

    Are you working towards a better understanding of neurodegenerative diseases or studying the function of the nervous system? See how you can make breakthroughs with imaging solutions from Leica…
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  • Organoids and 3D Cell Culture

    One of the most exciting recent advancements in life science research is the development of 3D cell culture systems, such as organoids, spheroids, or organ-on-a-chip models. A 3D cell culture is an…
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  • Virology

    Do your research interests focus on viral infection and disease? Find out how you can gain insights into virology with solutions for imaging and sample preparation from Leica Microsystems.
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  • Science Lab Topic: Fluorescence Microscopy

    From Organs to Tissues to Cells: Analyzing 3D Specimens with Widefield Microscopy

    Obtaining high-quality data and images from thick 3D samples is challenging using traditional widefield microscopy because of the contribution of out-of-focus light. In this webinar, Falco Krüger…
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  • Science Lab Topic: Widefield Microscopy

    Studying Human Brain Development and Disease

    Neural spheroids created from human induced pluripotent stem cells (iPSCs) provide effective and novel tools for studying brain development, as well as the underlying pathological mechanisms of…
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  • Science Lab Topic: Widefield Microscopy

    An Introduction to Computational Clearing

    Many software packages include background subtraction algorithms to enhance the contrast of features in the image by reducing background noise. The most common methods used to remove background noise…
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  • Science Lab Topic: Fluorescence Microscopy

    Image Gallery: THUNDER Imager

    To help you answer important scientific questions, THUNDER Imagers eliminate the out-of-focus blur that clouds the view of thick samples when using camera-based fluorescence microscopes. They achieve…
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  • Science Lab Topic: Basics in Microscopy

    Factors to Consider When Selecting a Research Microscope

    An optical microscope is often one of the central devices in a life-science research lab. It can be used for various applications which shed light on many scientific questions. Thereby the…
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  • Image courtesy of Dr. Stefan Finke, Friedrich-Loeffler- Institute, Riems, Germany.
    Science Lab Topic: Confocal Microscopy

    How Can Immunofluorescence Aid Virology Research?

    Modern virology research has become as crucial now as ever before due to the global COVID-19 pandemic. There are many powerful technologies and assays that virologists can apply to their research into…
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  • iPSC cells
    Science Lab Topic: Widefield Microscopy

    Studying Natural Killer (NK) Cells Derived from Induced Pluripotent Stem Cells (iPSC)

    The study of natural killer (NK) cells holds tremendous promise for developing novel immunotherapies. NK cells derived from induced pluripotent stem cells (iPSCs) can be used to create an easily…
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  • Science Lab Topic: Basics in Microscopy

    Getting Sharper 3D Images of Thick Biological Specimens with Widefield Microscopy

    Widefield fluorescence microscopy is often used to visualize structures in life science specimens and obtain useful information. With the use of fluorescent proteins or dyes, discrete specimen…
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  • Science Lab Topic: Fluorescence Microscopy

    IL-18 cytokine derived from the enteric nervous system is important for intestinal immunity

    Interleukin 18 (IL-18) is a proinflammatory cytokine, which induces cell-mediated immune reaction upon bacterial infection. In the intestine, it is known that IL-18 is produced in immune and…
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  • Science Lab Topic: Fluorescence Microscopy

    Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer

    Ovarian cancer is one of the most severe types of cancers that women can suffer from during their lifetimes. It is the cancer’s tendency for frequent relapses and drug resistance that leads to…
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  • Science Lab Topic: Widefield Microscopy

    Computational Clearing - Enhance 3D Specimen Imaging

    This webinar is designed to clarify crucial specifications that contribute to THUNDER Imagers' transformative visualization of 3D samples and improvements within a researcher's imaging-related…
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  • Science Lab Topic: Widefield Microscopy

    THUNDER Imagers: High Performance, Versatility and Ease-of-Use for your Everyday Imaging Workflows

    This webinar will showcase the versatility and performance of THUNDER Imagers in many different life science applications: from counting nuclei in retina sections and RNA molecules in cancer tissue…
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  • Science Lab Topic: Widefield Microscopy

    Evaluating Axon Regeneration After Brain or Spine Trauma of Mice

    Damaged nerve regeneration was investigated using mouse spinal cord sections treated with compounds that counter axon growth inhibitor (AGI) proteins. The sections were screened to find active and…
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  • Science Lab Topic: Fluorescence Microscopy

    Interview with Magali Mondin on THUNDER Imagers

    Magali Mondin, an engineer at the BIC (Bordeaux Imaging Center) in France, describes her experience using a THUNDER Imager in this interview. She had the opportunity to test extensively the THUNDER…
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  • Science Lab Topic: Widefield Microscopy

    Drosophila Testis Niche Stem Cells – Three Color Computational Clearing

    Differentiated living beings such as humans, but also a fruit fly or a plant, possess not only the differentiated cells which form specific tissues, but also those cells whose fate is not yet (or only…
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  • Science Lab Topic: Widefield Microscopy

    Alzheimer Plaques: fast Visualization in Thick Sections

    More than 60% of all diagnosed cases of dementia are attributed to Alzheimer’s disease. Typical of this disease are histological alterations in the brain tissue. So far, there is no cure for this…
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  • Science Lab Topic: Widefield Microscopy

    THUNDER Technology Note

    So far, widefield microscopy was not suitable to image larger volumes, since the contrast of the recorded fluorescence image is reduced by the background (BG) mainly originating from out of focus…
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