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Uncover the Hidden Complexity of Colon Cancer with Big Data
Colorectal cancer poses a significant health burden. While surgery is effective initially, some patients develop recurrent secondary disease with poor prognosis, necessitating advanced therapies like…
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Introduction to 21 CFR Part 11 for Electronic Records of Cell Culture
This article provides an introduction to the recommendations of 21 CFR Part 11 from the FDA, specifically focusing on the audit trail and user management in the context of cell-culture laboratories.…
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Mapping Tumor Immune Landscape with AI-Powered Spatial Proteomics
Spatial mapping of untreated tumors provides an overview of the tumor immune architecture, useful for understanding therapeutic responses. Immunocompetent murine models are essential for identifying…
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Deep Visual Proteomics Provides Precise Spatial Proteomic Information
Despite the availability of imaging methods and mass spectroscopy for spatial proteomics, a key challenge that remains is correlating images with single-cell resolution to protein-abundance…
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Spatial Analysis of Neuroimmune Interactions in Alzheimer’s Disease
Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neurofibrillary tangles, β-amyloid plaques, and neuroinflammation. These dysfunctions trigger or are exacerbated by…
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The Polarization Microscopy Principle
Polarization microscopy is routinely used in the material and earth sciences to identify materials and minerals on the basis of their characteristic refractive properties and colors. In biology,…
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A Guide to Spatial Biology
What is spatial biology, and how can researchers leverage its tools to meet the growing demands of biological questions in the post-omics era? This article provides a brief overview of spatial biology…
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An Introduction to Laser Microdissection
The heterogeneity of histological and biological specimens often requires isolation of specific single cells or cell groups from surrounding tissue before molecular biology analysis can be carried…
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神経細胞移動の分子的秘密を解き明かす
発達中の脳における特定部位への神経細胞の移動を調べるには、さまざまなアプローチを用いることができます。このウェビナーでは、オックスフォード大学の専門家が、神経発達過程における大脳皮質の機能層への神経細胞移動の分子メカニズムを解明するために使用している顕微鏡ツールとアッセイについて紹介します。これらのプロセスを理解することは、健全な脳の発達の理解を深め、神経発達障害の治療法を改善する可能性につながり…