Science Lab

Science Lab

Science Lab

ライカマイクロシステムズのナレッジポータルでは、顕微鏡の基礎から最先端技術まで、幅広い情報を提供しています。初心者から熟練者、研究者、医師の皆様まで、日々の研究や実験に役立つ内容となっております。チュートリアルやアプリケーションノートを活用し、学びながら探究心を刺激してください。さらに、コミュニティに参加することで、知見を共有し、新たな発見へとつなげましょう。お気軽に参加いただき、互いの専門知識を深め合う場としてご活用ください。
Shown is the DMi8 inverted microscope which is used for life-science research.

Factors to Consider When Selecting a Research Microscope

An optical microscope is often one of the central devices in a life-science research lab. It can be used for various applications which shed light on many scientific questions. Thereby the…

Infinity Optical Systems - From “Infinity Optics” to the Infinity Port

“Infinity Optics” is the concept of a light path with parallel rays between the objective and tube lens of a microscope [1]. Placing flat optical components into this “infinity space” which do not…
Some 2D measurements, e.g., lengths and areas, made on a PCB sample with a Leica measurement microscope using the Enersight software.

How to Select the Right Measurement Microscope

With a measurement microscope, users can measure the size and dimensions of sample features in both 2D and 3D, something crucial for inspection, QC, failure analysis, and R&D. However, choosing the…
Example of calibrating a microscope at a higher magnification value using a stage micrometer.

Microscope Calibration for Measurements: Why and How You Should Do It

Microscope calibration ensures accurate and consistent measurements for inspection, quality control (QC), failure analysis, and research and development (R&D). Calibration steps are described in this…
Spherulitic crystals of hippuric acid, a carboxylic acid found in urine, imaged with crossed polarizers showing so-called Maltese crosses. Spherulitic structures are formed by radial crystal growth starting from a central crystal nucleus. Image recorded with a DM4 P microscope using transmitted light, 20x Plan Fluotar objective, and polarizers.

A Guide to Polarized Light Microscopy

Polarized light microscopy (POL) enhances contrast in birefringent materials and is used in geology, biology, and materials science to study minerals, crystals, fibers, and plant cell walls.
Area of a printed circuit board (PCB) which was imaged with extended depth of field (EDOF) using digital microscopy.

顕微鏡を知る：被写界深度

顕微鏡において被写界深度は、凹凸の変化が⼤きい構造を持つ試料をピントがあったシャープに観察・撮像するために重要なパラメータです。被写界深度は、開⼝数、解像度、倍率の相関関係によって決定され、解像度とパラメータは反⽐例の関係にあります。被写界深度と解像度のバランスが最適になるように調整することができる顕微鏡もあります。
These images show the microstructure of a hard metal with 10% cobalt which is used for heavy-duty tools. The large increase in magnification of the right image (compared to the left) has a risk of being outside the useful range or, in other words, empty magnification.

What is Empty Magnification and How can Users Avoid it

The phenomenon of “empty magnification”, which can occur while using an optical, light, or digital microscope, and how it can be avoided is explained in this article. The performance of an optical…
Leitz Laborlux: Tartaric acids, polarization contrast

The Polarization Microscopy Principle

Polarization microscopy is routinely used in the material and earth sciences to identify materials and minerals on the basis of their characteristic refractive properties and colors. In biology,…
Microscope equipped with a K7 color CMOS camera for life-science and industry imaging applications.

Technical Terms for Digital Microscope Cameras and Image Analysis

Learn more about the basic principles behind digital microscope camera technologies, how digital cameras work, and take advantage of a reference list of technical terms from this article.
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