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Science Lab

Science Lab

Willkommen auf dem Wissensportal von Leica Microsystems. Hier finden Sie wissenschaftliches Forschungs- und Lehrmaterial rund um das Thema Mikroskopie. Das Portal unterstützt Anfänger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrer täglichen Arbeit und ihren Experimenten. Erkunden Sie interaktive Tutorials und Anwendungshinweise, entdecken Sie die Grundlagen der Mikroskopie ebenso wie High-End-Technologien. Werden Sie Teil der Science Lab Community und teilen Sie Ihr Fachwissen.

Image of confluent cells taken with phase contrast (left) and analyzed for confluency using AI (right).

AI Confluency Analysis for Enhanced Precision in 2D Cell Culture

This article explains how efficient, precise confluency assessment of 2D cell culture can be done with artificial intelligence (AI). Assessing confluency, the percentage of surface area covered,…

AI-based cell counting performed with a phase-contrast and fluorescence image using the Mateo FL microscope.

Precision and Efficiency with AI-Enhanced Cell Counting

This article describes the use of artificial intelligence (AI) for precise and efficient cell counting. Accurate cell counting is important for research with 2D cell cultures, e.g., cellular dynamics,…

AI-based transfection analysis (left) of U2OS cells which were transfected with a fluorescently labelled protein. A fluorescence image of the cells (right) is also shown. The analysis and imaging were performed with Mateo FL.

Leveraging AI for Efficient Analysis of Cell Transfection

This article explores the pivotal role of artificial intelligence (AI) in optimizing transfection efficiency measurements within the context of 2D cell culture studies. Precise and reliable…

Cell DIVE image of stromal remodeling around B cell follicles of follicular lymphoma patients. Stromal cells labeled with antibodies against desmin (red), SPARC (orange), vimentin (blue), and a-sma (yellow). Extracellular matrix labeled with antibody against lumican (cyan). B cells labeled with antibody against CD20 (green). Image credit: Dr. Andrea Radtke, Center for Advanced Tissue Imaging, NIAID, NIH

Empowering Spatial Biology with Open Multiplexing and Cell DIVE

Spatial biology and multiplexed imaging workflows have become important in immuno-oncology research. Many researchers struggle with study efficiency, even with effective tools and protocols. Here, we…

Evolved ARveo 8: Operating Room (OR) set-up.

Augmented Reality: Transformation von neurochirurgischen Verfahren

In diesem E-Book lernen Sie die großartigen Vorteile kennen, die Augmented Reality (AR) der Neurochirurgie bringt. Dieser umfassende Leitfaden enthält erklärende Videos, beantwortet brennende Fragen…

Laser Microdissection Protocols for Tissue and Cell Isolation - Download free eBook

In this Bio-protocol Selections, we present a collection of open-access, detailed methods papers using LCM to purify and isolate tissues and cells from plants, mouse embryos, cancer cells, neurons,…

40x magnification of organoids cluster taken on Mateo TL.Cell type: esophageal squamous carcinoma; scale bar 15µm. Courtesy of bioGenous, China.

Overcoming Observational Challenges in Organoid 3D Cell Culture

Learn how to overcome challenges in observing organoid growth. Read this article and discover new solutions for real-time monitoring which do not disturb the 3D structure of the organoids over time.

Particles observed on the surface of a particle trap which could be used for technical cleanliness during battery production.

Erkennung von Batteriepartikeln während des Produktionsprozesses

In diesem Artikel wird erläutert, wie die Partikelerkennung und -analyse von Batterien mit optischer Mikroskopie und Laserspektroskopie für eine schnelle, zuverlässige und kostengünstige…

THUNDER image of brain-capillary endothelial-like cells derived from human iPSCs (induced pluripotent stem cells) where cyan indicates nuclei and magenta tight junctions.

Rapid Check of Live Stem Cells in Cell-Culture Inserts set in Multi-Well Plates

See how efficient imaging of live iPSC stem cells within cell-culture inserts set in a multi-well plate can be done to evaluate the cells using a THUNDER Imager. Just read this article.