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Explore Alzheimer's Spatial Proteome with Big Data
Alzheimer's disease, a genetic and sporadic neurodegenerative condition, leads to cognitive decline in mid to late life, marked by β-amyloid plaques and tau tangles. With limited treatment options,…
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神経科学研究
神経変性疾患の理解向上に取り組んでいる、もしくは神経系の機能を研究をしていますか？ ライカマイクロシステムズのイメージングソリューションによってブレイクスルーを起こす方法をご覧ください。
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Spatial Analysis of Neuroimmune Interactions in Alzheimer’s Disease
Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neurofibrillary tangles, β-amyloid plaques, and neuroinflammation. These dysfunctions trigger or are exacerbated by…
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神経細胞移動の分子的秘密を解き明かす
発達中の脳における特定部位への神経細胞の移動を調べるには、さまざまなアプローチを用いることができます。このウェビナーでは、オックスフォード大学の専門家が、神経発達過程における大脳皮質の機能層への神経細胞移動の分子メカニズムを解明するために使用している顕微鏡ツールとアッセイについて紹介します。これらのプロセスを理解することは、健全な脳の発達の理解を深め、神経発達障害の治療法を改善する可能性につながり…
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Probing Human Alzheimer's Cortical Section using Spatial Multiplexing
Alzheimer’s disease (AD) is the most common neurodegenerative disease and is characterized by the progressive decline of cognitive function. Spatial profiling of AD brain may reveal cellular…
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Neuron Isolation in Spatial Context with Laser Microdissection (LMD)
After Alzheimer’s disease, Parkinson’s is the second most common progressive neurodegenerative disease. Before the first symptoms manifest, up to 70% of dopamine-releasing neurons in the mid-brain…
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How did Laser Microdissection enable Pioneering Neuroscience Research?
Dr. Marta Paterlini, a Senior Scientist at the Karolinska Institute, shares her experience of using laser microdissection (LMD) in groundbreaking research into adult human neurogenesis and offers…
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Laser Microdissection Protocols for Tissue and Cell Isolation - Download free eBook
In this Bio-protocol Selections, we present a collection of open-access, detailed methods papers using LCM to purify and isolate tissues and cells from plants, mouse embryos, cancer cells, neurons,…
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How do Cells Talk to Each Other During Neurodevelopment?
Professor Silvia Capello presents her group’s research on cellular crosstalk in neurodevelopmental disorders, using models such as cerebral organoids and assembloids.
