Science Lab

Science Lab

Science Lab

ライカマイクロシステムズのナレッジポータルでは、顕微鏡の基礎から最先端技術まで、幅広い情報を提供しています。初心者から熟練者、研究者、医師の皆様まで、日々の研究や実験に役立つ内容となっております。チュートリアルやアプリケーションノートを活用し、学びながら探究心を刺激してください。さらに、コミュニティに参加することで、知見を共有し、新たな発見へとつなげましょう。お気軽に参加いただき、互いの専門知識を深め合う場としてご活用ください。
UC Enuity

Improve Your Ultramicrotomy Workflow with Automated Sectioning

Discover advanced digital ultramicrotomy tools for fast and accurate automated sectioning. Learn about autoalignment, and efficient sample trimming leveraging 3D µCT data. See application examples…
AI-based transfection analysis (left) of U2OS cells which were transfected with a fluorescently labelled protein. A fluorescence image of the cells (right) is also shown. The analysis and imaging were performed with Mateo FL.

Leveraging AI for Efficient Analysis of Cell Transfection

This article explores the pivotal role of artificial intelligence (AI) in optimizing transfection efficiency measurements within the context of 2D cell culture studies. Precise and reliable…
AI-based cell counting performed with a phase-contrast and fluorescence image using the Mateo FL microscope.

Precision and Efficiency with AI-Enhanced Cell Counting

This article describes the use of artificial intelligence (AI) for precise and efficient cell counting. Accurate cell counting is important for research with 2D cell cultures, e.g., cellular dynamics,…
Image of confluent cells taken with phase contrast (left) and analyzed for confluency using AI (right).

AI Confluency Analysis for Enhanced Precision in 2D Cell Culture

This article explains how efficient, precise confluency assessment of 2D cell culture can be done with artificial intelligence (AI). Assessing confluency, the percentage of surface area covered,…
Cell DIVE image of stromal remodeling around B cell follicles of follicular lymphoma patients. Stromal cells labeled with antibodies against desmin (red), SPARC (orange), vimentin (blue), and a-sma (yellow). Extracellular matrix labeled with antibody against lumican (cyan). B cells labeled with antibody against CD20 (green). Image credit: Dr. Andrea Radtke, Center for Advanced Tissue Imaging, NIAID, NIH

Empowering Spatial Biology with Open Multiplexing and Cell DIVE

Spatial biology and multiplexed imaging workflows have become important in immuno-oncology research. Many researchers struggle with study efficiency, even with effective tools and protocols. Here, we…
Image of murine dopaminergic neurons which have been marked for laser microdissection (LMD).

Neuron Isolation in Spatial Context with Laser Microdissection (LMD)

After Alzheimer’s disease, Parkinson’s is the second most common progressive neurodegenerative disease. Before the first symptoms manifest, up to 70% of dopamine-releasing neurons in the mid-brain…

How did Laser Microdissection enable Pioneering Neuroscience Research?

Dr. Marta Paterlini, a Senior Scientist at the Karolinska Institute, shares her experience of using laser microdissection (LMD) in groundbreaking research into adult human neurogenesis and offers…

AI-Powered Multiplexed Image Analysis to Explore Colon Adenocarcinoma

In this application note, we demonstrate a spatial biology workflow via an AI-powered multiplexed image analysis-based exploration of the tumor immune microenvironment in colon adenocarcinoma.

Laser Microdissection Protocols for Tissue and Cell Isolation - Download free eBook

In this Bio-protocol Selections, we present a collection of open-access, detailed methods papers using LCM to purify and isolate tissues and cells from plants, mouse embryos, cancer cells, neurons,…
Beckman Coulter LinkBeckman Coulter LogoGenedata LinkIDBS LogoIDBS LinkIDBS LogoAbcam Limited LinkAbcam Limited LogoMolecular Devices LinkMolecular Devices LogoPhenomenex LinkPhenomenex LogoSciex LinkSciex LogoAldevron LinkAldevron LogoIDT LinkIDT Logo
Scroll to top