Life Science Research
Life Science Research
This is the place to expand your knowledge, research capabilities, and practical applications of microscopy in various scientific fields. Learn how to achieve precise visualization, image interpretation, and research advancements. Find insightful information on advanced microscopy, imaging techniques, sample preparation, and image analysis. Topics covered include cell biology, neuroscience, and cancer research with a focus on cutting-edge applications and innovations.
Mapping Tumor Immune Landscape with AI-Powered Spatial Proteomics
Spatial mapping of untreated tumors provides an overview of the tumor immune architecture, useful for understanding therapeutic responses. Immunocompetent murine models are essential for identifying…
Deep Visual Proteomics Provides Precise Spatial Proteomic Information
Despite the availability of imaging methods and mass spectroscopy for spatial proteomics, a key challenge that remains is correlating images with single-cell resolution to protein-abundance…
Spatial Analysis of Neuroimmune Interactions in Alzheimer’s Disease
Alzheimer’s disease (AD) is a complex neurodegenerative disorder characterized by neurofibrillary tangles, β-amyloid plaques, and neuroinflammation. These dysfunctions trigger or are exacerbated by…
The Polarization Microscopy Principle
Polarization microscopy is routinely used in the material and earth sciences to identify materials and minerals on the basis of their characteristic refractive properties and colors. In biology,…
A Guide to Spatial Biology
What is spatial biology, and how can researchers leverage its tools to meet the growing demands of biological questions in the post-omics era? This article provides a brief overview of spatial biology…
An Introduction to Laser Microdissection
The heterogeneity of histological and biological specimens often requires isolation of specific single cells or cell groups from surrounding tissue before molecular biology analysis can be carried…
Revealing Neuronal Migration’s Molecular Secrets
Different approaches can be used to investigate neuronal migration to their niche in the developing brain. In this webinar, experts from The University of Oxford present the microscopy tools and…
Molecular Biology Analysis facilitated with Laser Microdissection (LMD)
Extracting biomolecules, proteins, nucleic acids, lipids, and chromosomes, as well as extracting and manipulating cells and tissues with laser microdissection (LMD) enables insights to be gained into…
Probing Human Alzheimer's Cortical Section using Spatial Multiplexing
Alzheimer’s disease (AD) is the most common neurodegenerative disease and is characterized by the progressive decline of cognitive function. Spatial profiling of AD brain may reveal cellular…
