Life Science Research

This is the place to expand your knowledge, research capabilities, and practical applications of microscopy in various scientific fields. Learn how to achieve precise visualization, image interpretation, and research advancements. Find insightful information on advanced microscopy, imaging techniques, sample preparation, and image analysis. Topics covered include cell biology, neuroscience, and cancer research with a focus on cutting-edge applications and innovations.

Spherulitic crystals of hippuric acid, which were imaged with a Leica microscope using crossed polarizers, showing so-called Maltese crosses.

A Guide to Polarized Light Microscopy

Polarized light microscopy (POL) enhances contrast in birefringent materials and is used in geology, biology, and materials science to study minerals, crystals, fibers, and plant cell walls.

Fluorescence microscope image of a life-science specimen

An Introduction to Fluorescence

This article gives an introduction to fluorescence and photoluminescence, which includes phosphorescence, explains the basic theory behind them, and how fluorescence is used for microscopy.

A Guide to Darkfield Microscopes

A darkfield microscope offers a way to view the structures of many types of biological specimens in greater contrast without the need of stains.

A Guide to Phase Contrast

A phase contrast light microscope offers a way to view the structures of many types of biological specimens in greater contrast without the need of stains.