Science Lab

Science Lab

Science Lab

Willkommen auf dem Wissensportal von Leica Microsystems. Hier finden Sie wissenschaftliches Forschungs- und Lehrmaterial rund um das Thema Mikroskopie. Das Portal unterstützt Anfänger, erfahrene Praktiker und Wissenschaftler gleichermaßen bei ihrer täglichen Arbeit und ihren Experimenten. Erkunden Sie interaktive Tutorials und Anwendungshinweise, entdecken Sie die Grundlagen der Mikroskopie ebenso wie High-End-Technologien. Werden Sie Teil der Science Lab Community und teilen Sie Ihr Fachwissen.

Phasenkontrast und Mikroskopie

Dieser Artikel erklärt den Phasenkontrast, eine optische Mikroskopietechnik, die feine Details von ungefärbten, transparenten Proben sichtbar macht, die mit gewöhnlicher Hellfeldbeleuchtung schwer zu…
Microscope image of cultured cells at the bottom of a dish.

How to do a Proper Cell Culture Quick Check

In order to successfully work with mammalian cell lines, they must be grown under controlled conditions and require their own specific growth medium. In addition, to guarantee consistency their growth…

FluoSync - a Fast & Gentle Method for Unmixing Multicolor Images

In this white paper, we focus on a fast and reliable method for obtaining high-quality multiplex images in fluorescence microscopy. FluoSync combines an existing method for hybrid unmixing with…
Living HeLa cells stained with WGA-488 (yellow), SPY-Actin (cyan), and SiR-Tubulin (magenta). Instant Computational Clearing (ICC) was applied.

How to Perform Dynamic Multicolor Time-Lapse Imaging

Live-cell imaging sheds light on diverse cellular events. As many of these events have fast dynamics, the microscope imaging system must be fast enough to record every detail. One major advantage of…
Untreated Hela Kyoto cells stained to show the nucleus (Hoechst, blue), the cis-golgi matrix protein GM130 (AF488, green), and the trans-golgi network membrane protein TGN46 (AF647, red).

Golgi Organizational Changes in Response to Cell Stress

In this video on demand, our special guest George Galea from EMBL Heidelberg will look at HeLa Kyoto cells treated with various chemotherapeutic agents to investigate their effect on the Golgi complex…
Pancreatic ductal adenocarcinoma tissue section imaged with Cell DIVE

Multiplexed Imaging Types, Benefits and Applications

Multiplexed imaging is an emerging and exciting way to extract information from human tissue samples by visualizing many more biomarkers than traditional microscopy. By observing many biomarkers…
3D Reconstruction of brain slide image_Mica

3D Tissue Imaging: From Fast Overview To High Resolution With One Click

3D Tissue imaging is a widespread discipline in the life sciences. Researchers use it to reveal detailed information of tissue composition and integrity, to make conclusions from experimental…
MDCK cysts on day 9

How To Perform Fast & Stable Multicolor Live-Cell Imaging

With the help of live-cell imaging researchers gain insights into dynamic processes of living cells up to whole organisms. This includes intracellular as well as intercellular activities. Protein or…
Image of a single slice taken from a zebrafish heart showing the ventricle with an injury in the lower area. Nuclei of all cells are indicated with blue, nuclei of the cardiomyocyte heart muscle cells with green, and the proliferating cells with red. Courtesy of Laura Peces-Barba Castaño, Max Planck Institute for Heart and Lung Research, Germany.

Imaging of Cardiac Tissue Regeneration in Zebrafish

Learn how to image cardiac tissue regeneration in zebrafish focusing on cell proliferation and response during recovery with Laura Peces-Barba Castaño from the Max Planck Institute.
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