Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

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What is Photomanipulation?
The term photomanipulation describes a wide range of techniques that enable the microscopist the transition from passive observer to instigator of…
May 15, 2017
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Photoactivatable, photoconvertible, and photoswitchable Fluorescent Proteins
Fluorescent proteins (FPs) such as GFP, YFP or DsRed are powerful tools to visualize cellular components in living cells. Nevertheless, there are…
May 04, 2017
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Optogenetic Toolkit Goes Multicolor
Optogenetics is a technique that allows scientists to control neurons’ electrical activity with light by engineering them to express light-sensitive…
Feb 25, 2014
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Optogenetics
Optogenetics is a technique that allows light-controlled responses of transfected cells. The cells are genetically modified by introduction of genes…
Oct 29, 2012
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Fluorescence Recovery after Photobleaching (FRAP) and its Offspring
FRAP (Fluorescence recovery after photobleaching) can be used to study cellular protein dynamics: For visualization the protein of interest is fused…
Nov 23, 2011
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Latest Articles

What is Photomanipulation?

Photoactivatable, photoconvertible, and photoswitchable Fluorescent Proteins

Optogenetic Toolkit Goes Multicolor

Optogenetics

Fluorescence Recovery after Photobleaching (FRAP) and its Offspring