
Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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FluoSync - a Fast & Gentle Method for Unmixing Multicolour Images
In this white paper, we focus on a fast and reliable method for obtaining high-quality multiplex images in fluorescence microscopy. FluoSync combines an existing method for hybrid unmixing with…
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Harnessing Microfluidics to Maintain Cell Health During Live-Cell Imaging
VIDEO ON DEMAND - In this episode of MicaCam, we will use microfluidics to explore the effect of shear stress on cell morphology, examine the effect of nutrient replenishment on cellular growth during…
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How to Perform Dynamic Multicolor Time-Lapse Imaging
Live-cell imaging sheds light on diverse cellular events. As many of these events have fast dynamics, the microscope imaging system must be fast enough to record every detail. One major advantage of…
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Following Multiple Events during Staurosporine Apoptosis
VIDEO ON DEMAND - In this episode of MicaCam, we show how adding additional markers to an apoptosis kit can markedly increase the amount of information a researcher can obtain from the same…
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Golgi Organizational Changes in Response to Cell Stress
VIDEO ON DEMAND - In this episode of MicaCam, our special guest George Galea from EMBL Heidelberg will look at HeLa Kyoto cells treated with various chemotherapeutic agents to investigate their effect…
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AI-Enabled Spatial Analysis of Complex 3D Datasets
VIDEO ON DEMAND - This edition of MicaCam offers practical advice on the extraction of publication grade insights from microscopy images. Our special guest Luciano Lucas (Leica Microsystems) will…
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3D Tissue Imaging: From Fast Overview To High Resolution With One Click
3D Tissue imaging is a widespread discipline in the life sciences. Researchers use it to reveal detailed information of tissue composition and integrity, to make conclusions from experimental…
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How To Perform Fast & Stable Multicolor Live-Cell Imaging
With the help of live-cell imaging researchers gain insights into dynamic processes of living cells up to whole organisms. This includes intracellular as well as intercellular activities. Protein or…
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Cardiomyocyte Proliferation Upon Heart Injury in Zebrafish
VIDEO ON DEMAND - This edition of MicaCam focuses on the study of the zebrafish (Danio rerio) whose heart cells can fully regenerate after injury.