Science Lab

Learn. Share. Contribute. The knowledge portal of Leica Microsystems. Find scientific research and teaching material on the subject of microscopy. The portal supports beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies. Become part of the Science Lab community and share your expertise.

Be Confident in your Results with Cell DIVE Validated Antibodies

The Cell DIVE System includes a carefully curated list of hundreds of commercially available antibodies validated to offer optimal specificity and sensitivity in multiplexed imaging. That validation…

Intraoperative OCT in Retinal Procedures

In their white paper the surgical team at Retina Clinic in São Paulo provide insight into cases of complex retinal surgery in which OCT has provided helpful additional information which has on…

Optimal Visualization in Brain Surgery

This case study “Treatment of the Galassi type III arachnoid cyst with the M530 OHX surgical microscope from Leica Microsystems” documents the procedure step by step and shows the visualization…

Benefits of Combining STED and Lifetime

In this interview, Professor Alberto Diaspro talks about the advantages of the White Light Laser and the TauSTED capabilities of STELLARIS 8 STED. He speaks about his experience with the confocal…

Spectroscopic Evaluation of Red Blood Cells

Hemoglobinopathies are a major healthcare problem. This study presents a possible diagnostic tool for thalassemia which is based on confocal spectroscopy. This approach exploits spectral detection and…

How to use a Surgical Microscope as an Operating Room Nurse

Surgical microscopes play an essential role in the modern microsurgery procedures. It provides the surgeon, assistant and operating room staff with a magnified and illuminated high-quality image of…

HeLa Kyoto cells (HKF1, H2B-mCherry, alpha Tubulin, mEGFP). Left image: Maximum projection of a z-stack prior to ICC and LVCC. Right image: Maximum projection of a mosaic z-stack after ICC and LVCC.

How to Improve Live Cell Imaging with Coral Life

For live-cell CLEM applications, light microscopy imaging is a critical step for identifying the right cell in the right state at the right time. In this article, Leica experts share their insights on…

The Cryo-CLEM Journey

This article describes the Cryo-CLEM technology and the benefits it can provide for scientists. Additionally, some scientific publications are highlighted. Recent developments in cryo electron…

Clinical Symposium on OCT-guided Cornea Surgery

In this recording Prof. Mehta from Singapore National Eye Centre and Prof. Fontana from Santa Maria Nuova Hospital in Regio Emilia, Italy, share their expertise on corneal surgery. They present PK,…