
Science Lab
Science Lab
Learn. Share. Contribute. The knowledge portal of Leica Microsystems. Find scientific research and teaching material on the subject of microscopy. The portal supports beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies. Become part of the Science Lab community and share your expertise.
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From Bench to Beam: A Complete Correlative Cryo Light Microscopy Workflow
In the webinar entitled "A Multimodal Vitreous Crusade, a Cryo Correlative Workflow from Bench to Beam" a team of experts discusses the exciting world of correlative workflows for structural biology…
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Depth of Field in Microscope Images
For microscopy imaging, depth of field is an important parameter when needing sharp images of sample areas with structures having significant changes in depth. In practice, depth of field is…
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Dive into Pancreatic Cancer Research with Big Data
Pancreatic cancer, with a mortality rate near 40%, is challenging to treat due to its proximity to major organs. This story explores the complex biology of pancreatic ductal adenocarcinoma (PDAC),…
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Uncover the Hidden Complexity of Colon Cancer with Big Data
Colorectal cancer poses a significant health burden. While surgery is effective initially, some patients develop recurrent secondary disease with poor prognosis, necessitating advanced therapies like…
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Introduction to 21 CFR Part 11 for Electronic Records of Cell Culture
This article provides an introduction to the recommendations of 21 CFR Part 11 from the FDA, specifically focusing on the audit trail and user management in the context of cell-culture laboratories.…
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Overcoming Challenges with Microscopy when Imaging Moving Zebrafish Larvae
Zebrafish is a valuable model organism with many beneficial traits. However, imaging a full organism poses challenges as it is not stationary. Here, this case study shows how zebrafish larvae can be…
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A Guide to Neuroscience Research
Are you working towards a better understanding of neurodegenerative diseases or studying the function of the nervous system? See how you can make breakthroughs with imaging solutions from Leica…
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Mapping Tumor Immune Landscape with AI-Powered Spatial Proteomics
Spatial mapping of untreated tumors provides an overview of the tumor immune architecture, useful for understanding therapeutic responses. Immunocompetent murine models are essential for identifying…
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Aneurysm Clipping: Assessing Perforators in Real-Time with AR Fluorescence
This article covers two aneurysm clipping cases highlighting the clinical benefits of GLOW800 Augmented Reality Fluorescence application in neurosurgery, based on insights from Prof. Tohru Mizutani,…