Science Lab

Learn. Share. Contribute. The knowledge portal of Leica Microsystems. Find scientific research and teaching material on the subject of microscopy. The portal supports beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies. Become part of the Science Lab community and share your expertise.

Mouse brain slice which was immunostained with GFAP-A647 and imaged using a THUNDER Imager Tissue. Courtesy of H. Xu, University of Pennsylvania, Philadelphia, USA.

A Guide to Neuroscience Research

Neuroscience often requires investigating challenging specimens to better understand the nervous system and disorders. Leica microscopes helps neuroscientists obtain insights into neuronal functions.

Patch pipette touching a murine hippocampal neuron. Image courtesy of A. Aguado, Ruhr University Bochum, Germany.

What is the Patch-Clamp Technique?

This article gives an introduction to the patch-clamp technique and how it is used to study the physiology of ion channels for neuroscience and other life-science fields.