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Cryo-electron micrographs of subviral particles of a common cold virus bound to liposomes, acquired under low dose conditions at 300 kV with a CCD-camera.

Immersion Freezing for Cryo-Transmission Electron Microscopy: Applications

A well established usage case for cryo-TEM is three-dimensional reconstruction of isolated macromolecules, virus particles, or filaments. These approaches are based on averaging of repetitive…