Science Lab

Learn. Share. Contribute. The knowledge portal of Leica Microsystems. Find scientific research and teaching material on the subject of microscopy. The portal supports beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies. Become part of the Science Lab community and share your expertise.

Cellular microtubule network in a fibroblast cell.

How to Prepare your Specimen for Immunofluorescence Microscopy

Immunofluorescence (IF) is a powerful method for visualizing intracellular processes, conditions and structures. IF preparations can be analyzed by various microscopy techniques (e.g. CLSM,…

Single timepoint of a drosophilia embryo, 3D object detection

Examining Critical Developmental Events in High-Definition

Extended live cell imaging of embryo development requires a delicate balance between light exposure, temporal resolution and spatial resolution to maintain cells’ viability. Compromises between the…

How Industrial Applications Benefit from Fluorescence Microscopy

Watch this free webinar to know more about what you can do with fluorescence microscopy for industrial applications. We will cover a wide range of investigations where fluorescence contrast offers new…

Spectroscopic Evaluation of Red Blood Cells

Hemoglobinopathies are a major healthcare problem. This study presents a possible diagnostic tool for thalassemia which is based on confocal spectroscopy. This approach exploits spectral detection and…

How Augmented Reality is Transforming Vascular Neurosurgery

Augmented Reality is changing surgery, with new information helping to improve the precision and safety of procedures. This is especially true in vascular neurosurgery where Augmented Reality is…

Improvement of Imaging Techniques to Understand Organelle Membrane Cell Dynamics

Understanding cell functions in normal and tumorous tissue is a key factor in advancing research of potential treatment strategies and understanding why some treatments might fail. Single-cell…

How FLIM Microscopy Helps to Detect Microplastic Pollution

The use of autofluorescence in biological samples is a widely used method to gain detailed knowledge about systems or organisms. This property is not only found in biological systems, but also…

Oncological Reconstructive Surgery with the Leica M530 OHX Microscope

Precision is essential in oncological reconstructive surgery, in particular when it relies on free flap techniques. Microsurgical microscopes provide optimal visualization and help streamline the…

Oncological Reconstructive Surgery: Why Use a Microscope

Recent advances in microsurgery are enhancing breast reconstruction for oncology patients, allowing both functional and aesthetic rehabilitation. More and more surgeons are adopting surgical…