Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

Staining is crucial to revealing details in the specimens.

H&E Staining in Microscopy

If we consider the role of microscopy in pathologists’ daily routines, we often think of the diagnosis. While microscopes indeed play a crucial role at this stage of the pathology lab workflow, they…

How to Benefit from Digital Cytopathology

If you have thought of digital cytopathology as characterized by the digitization of glass slides, this webinar with Dr. Alessandro Caputo from the University Hospital of Salerno, Italy will broaden…

Factors for Selecting Clinical Microscopes

If you are considering the purchase of new clinical microscopes for yourself or your team, you will think about many options, vendors, and microscope models. Here are some tips to help you come to the…

Histopathological sample, 40x magnification

Clinical Microscopy: Considerations on Camera Selection

The need for images in pathology laboratories has significantly increased over the past few years, be it in histopathology, cytology, hematology, clinical microbiology, or other applications. They…

The Time to Diagnosis is Crucial in Clinical Pathology

Abnormalities in tissues and fluids - that’s what pathologists are looking for when they examine specimens under the microscope. What they see and deduce from their findings is highly influential, as…

Perform Microscopy Analysis for Pathology Ergonomically and Efficiently

The main performance features of a microscope which are critical for rapid, ergonomic, and precise microscopic analysis of pathology specimens are described in this article. Microscopic analysis of…

Epoxy Resin Embedding of Animal and Human Tissues for Pathological Diagnosis and Research

Application Note for Leica EM AMW - The tissues were fixed in the modified Karnovsky fixative generally by immersion overnight (at minimum 4h at room temperature). Then pieces of approx. 1mm3 were cut…

Exemplary Specimen Overviews of a customer sample with many tumor areas being dissected

Workflows & Protocols: Laser Microdissection for Pathology and Cancer Research

Tumor development results from mutations in our DNA. For their deeper analysis, cancer researchers have to dissect the relevant tissue areas. Here we report the reason why laser microdissection is a…

Pathology Overcomes Boundaries – Interactive Microscope System Facilitates Training of Pathologists in Developing Countries

"The lack of pathological examinations is one of the most pressing issues of medical care in developing countries." Dr. Roberto Monaco, pathologist in Neaples, knows the disastrous consequences from…