Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

Latest Articles

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Cardiomyocyte Proliferation Upon Heart Injury in Zebrafish
This edition of MicaCam focuses on the study of the zebrafish (Danio rerio) whose heart cells can fully regenerate after injury.
Jun 09, 2022
Webinar
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Wt1 Genes Can Induce a Cardiomyocyte to Epicardial-like Cell Fate Transition
From this study, it was concluded that Wt1 plays a yet undescribed role for cardiomyocyte differentiation by repressing chromatin opening at specific…
Apr 27, 2022
Abstract
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Fish and Chips Sheet into the Light
The zebrafish larval brain is small and contains about 1 million times less neurons than the human counterpart. The neural circuitry and the general…
May 05, 2021
Abstract
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High-Resolution 3D Imaging of Whole Organ after Clearing
Zebrafish testis has become a powerful model for reproductive biology of teleostean fishes and other vertebrates and encompasses multiple applications…
May 08, 2018
Abstract
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DLS Sample Preparation: Using U-Shaped Glass Capillaries for Sample Mounting
The TCS SP8 DLS microscope system from Leica Microsystems is an innovative concept which integrates the Light Sheet Microscopy technology into the SP8…
Dec 06, 2017
Story
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Real Time Observation of Neutrophil White Blood Cell Recruitment to Bacterial Infection In Vivo
The zebrafish (Danio rerio) is an emerging vertebrate model organism to study infection. The transparent larva comprises a fully functional innate…
Jul 27, 2017
Story
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Work More Efficiently in Developmental Biology With Stereo Microscopy: Zebrafish, Medaka, and Xenopus
Among the aquatic model organisms used in molecular and developmental biology the most prominent are the zebrafish (genus species: Danio rerio),…
Oct 27, 2016
Story
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Infection of Zebrafish Embryos with Intracellular Bacterial Pathogens
Transparent zebrafish embryos have proved useful model hosts to visualize and functionally study interactions between innate immune cells and…
Feb 05, 2016
Abstract
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Patch Clamp Recordings from Embryonic Zebrafish Mauthner Cells
Mauthner cells (M-cells) are large reticulospinal neurons located in the hindbrain of teleost fish. They are key neurons involved in a characteristic…
Oct 11, 2013
Abstract
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Organ Regeneration: An Unlikely Fish Tale
Spectacular discoveries in cardiac tissue regeneration are rapidly moving researchers closer to the goal of harnessing regenerative techniques to…
Jun 20, 2013
Story
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Find the Needle in the Haystack
The obvious has been explored. These days, biologists strive to identify and analyze hidden and rare events. The task is tackled by automatically…
Aug 03, 2011
Tutorial
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Deep Tissue Imaging
Developmental biology using Multiphoton microscopy with OPO. To gain new insight into the fundamental control of cell response to physical changes…
Nov 01, 2010
Story

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Latest Articles

Cardiomyocyte Proliferation Upon Heart Injury in Zebrafish

Wt1 Genes Can Induce a Cardiomyocyte to Epicardial-like Cell Fate Transition

Fish and Chips Sheet into the Light

High-Resolution 3D Imaging of Whole Organ after Clearing

DLS Sample Preparation: Using U-Shaped Glass Capillaries for Sample Mounting

Real Time Observation of Neutrophil White Blood Cell Recruitment to Bacterial Infection In Vivo

Work More Efficiently in Developmental Biology With Stereo Microscopy: Zebrafish, Medaka, and Xenopus

Infection of Zebrafish Embryos with Intracellular Bacterial Pathogens

Patch Clamp Recordings from Embryonic Zebrafish Mauthner Cells

Organ Regeneration: An Unlikely Fish Tale

Find the Needle in the Haystack

Deep Tissue Imaging