
Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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Open Multiplexing: Transforming Tissue Research with Cell DIVE
Watch this webinar to discover how open multiplexing adapts to meet the needs of your multiplexing imaging study.
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Identifying Fibroblast Phenotypes with Multiplex Imaging
Identifying fibroblasts phenotypes can help researchers understand the relationship between distinct diseases and inflammation mechanisms. Fibroblasts perform a wide variety of immune and repair roles…
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Multiplexed Imaging Types, Benefits and Applications
Multiplexed imaging is an emerging and exciting way to extract information from human tissue samples by visualizing many more biomarkers than traditional microscopy. By observing many biomarkers…
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Tumor MHC Expression and Intralesional IL2 Response in Melanoma
Genomics profiling and Cell DIVE multiplex imaging allows researchers to understand the immune cell phenotypes that most strongly predict response to IL2 immunotherapy in melanoma patients suffering…
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Multiplex Imaging Reveals Survival Markers after Cancer Care
Colorectal cancer is a high incidence and high mortality cancer. Currently, postoperative chemotherapy benefits only a minority of patients, and thus, new tools are necessary to screen patients and…
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Hyperplex Cancer Tissue Analysis at Single Cell Level with Cell DIVE
The ability to study how lymphoma cell heterogeneity is influenced by the cells’ response to their microenvironment, especially at the mutational, transcriptomic, and protein levels. Protein…
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Visualizing the Mitotic Spindle in Cancer Cells
This article demonstrates how this research is aided by visualizing more details of mitotic spindles in Ewing Sarcoma cells using the THUNDER Imager Tissue and Large Volume Computational Clearing…
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Simplifying the Cancer Biology Image Analysis Workflow
As cancer biology data sets grow, so do the challenges in microscopy image analysis. Aivia experts cover how to overcome these challenges with AI.
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Imaging of Anti-Cancer Drug Uptake in Spheroids using DLS
Spheroid 3D cell culture models mimic the physiology and functions of living tissues making them a useful tool to study tumor morphology and screen anti-cancer drugs. The drug AZD2014 is a recognized…