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Science Lab

Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

RPE65 Gene Therapy Subretinal Injection: Benefits of Intraoperative OCT

Discover how RPE65 gene therapy subretinal injection procedures in patients with Leber congenital amaurosis is supported by intraoperative Optical Coherence Tomography.
Applying dispersive viscoelastic to coat the anterior chamber. Image courtesy of Arsham Sheybani, MD, Washington University School of Medicine.

Dislocated Cataract Angle Closure Aided by Intraoperative OCT

Learn how a dislocated cataract was treated with angle closure assisted by intraoperative OCT to achieve long-term good results without future lens dislocation.
Dr. Sheybani places the new subconjunctival stent in the anterior chamber. Images courtesy of Arsham Sheybani, MD.

Glaucoma Stent Revision Surgery Guided by Intraoperative OCT

Learn about a glaucoma subconjunctival stent revision guided by intraoperative OCT and the important role it plays to ensure the best outcome.
Prof. Nikolaos Bechrakis uses the Proveo 8 ceiling mounted microscope with EnFocus intraoperative OCT. Images provided by Prof. Nikolaos Bechrakis.

Posterior Segment Surgery: Benefits of Utilizing Intraoperative OCT

Learn about the value of intraoperative optical coherence tomography in posterior segment surgery to precisely locate, evaluate and manage pathologies.
Microscope view (left). The intraoperative OCT images (right) allowed Prof. Bechrakis to see exactly where the previous scars were to avoid the area where the previous trephination was performed. Images provided by Prof. Nikolaos Bechrakis.

Intraoperative OCT-Assisted Corneal Transplant Procedures

Learn about the use of intraoperative optical coherence tomography in corneal transplantation and how it facilitates the adaptation of the donor cornea.
Dr. Ozana Moraru shares two primary open-angle glaucoma cases in which trabeculectomy bleb needling was performed using the Leica M844 microscope with EnFocus intraoperative OCT. Image courtesy of Dr. Ozana Moraru.

How Intraoperative OCT Helps Gain Greater Insight in Glaucoma Surgery

Learn about the use of intraoperative Optical Coherence Tomography in glaucoma surgery and how it helps see subsurface tissue details.
Intraoperative OCT-assisted complex cataract surgery. Image courtesy of Dr. Ozana Moraru.

Ophthalmology: Visualization in Complex Cataract Surgery

Learn about the use of intraoperative Optical Coherence Tomography in cataract surgery and how it supports both standard and complex cataract surgery cases.
Fundus photo depicting epiretinal membrane with lamellar macular hole. Image courtesy of Robert A. Sisk, MD, FACS, Cincinnati Eye Institute.

Improve Macular Hole Surgery with Optical Coherence Tomography

A case study on the use of intraoperative OCT during macular hole surgery for pediatric lamellar macular hole repair and how it provides valuable real-time information.
Corneal perforation with iris plugging shown on the intraoperative OCT. Images provided by Mr. David Anderson

Ocular Perforation and Trauma Surgery

Learn about the use of intraoperative Optical Coherence Tomography (OCT) in ocular perforation and trauma surgery, and how it supports assessment and repair.
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