Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

Dr. Ozana Moraru shares two primary open-angle glaucoma cases in which trabeculectomy bleb needling was performed using the Leica M844 microscope with EnFocus intraoperative OCT. Image courtesy of Dr. Ozana Moraru.

How Intraoperative OCT Helps Gain Greater Insight in Glaucoma Surgery

Learn about the use of intraoperative Optical Coherence Tomography in glaucoma surgery and how it helps see subsurface tissue details.

Intraoperative OCT-assisted complex cataract surgery. Image courtesy of Dr. Ozana Moraru.

Ophthalmology: Visualization in Complex Cataract Surgery

Learn about the use of intraoperative Optical Coherence Tomography in cataract surgery and how it supports both standard and complex cataract surgery cases.

Fundus photo depicting epiretinal membrane with lamellar macular hole. Image courtesy of Robert A. Sisk, MD, FACS, Cincinnati Eye Institute.

Improve Macular Hole Surgery with Optical Coherence Tomography

A case study on the use of intraoperative OCT during macular hole surgery for pediatric lamellar macular hole repair and how it provides valuable real-time information.

Corneal perforation with iris plugging shown on the intraoperative OCT. Images provided by Mr. David Anderson

Ocular Perforation and Trauma Surgery

Learn about the use of intraoperative Optical Coherence Tomography (OCT) in ocular perforation and trauma surgery, and how it supports assessment and repair.

Corneal transplantation. Image courtesy of Mr. David Anderson.

Ophthalmology Case Study: Corneal Transplantation

Learn about the use of intraoperative Optical Coherence Tomography in Corneal Transplantation and how it helps achieve correct positioning of donor tissue.

The intraoperative OCT showed the ellipsoid had separated from the inner retina with focal attachment to the retinal pigment epithelium (RPE). Images provided by Mr. Robert Henderson

Utility of Intraoperative OCT in Sub-Retinal Gene Therapy

Discover a case study on the use of intraoperative OCT for pediatric gene therapy and how it supports bleb placement and verifying the foveal contour.

Diffuse retinal degeneration with relative macular sparing.

Ophthalmic Gene Therapy Subretinal Injection

Case study on the use of intraoperative OCT for Leber congenital amaurosis macular repair and ophthalmic gene therapy subretinal injection.

Clinical Symposium on OCT-Guided Retina Surgery

In this recording Prof. Tan from Singapore National Eye Centre and Dr. Català from Sant Joan de Déu Barcelona Children’s Hospital share their expertise on retinal surgery with intraoperative OCT from…

Intraoperative OCT in Retinal Procedures

The surgical team at Retina Clinic in São Paulo, Brazil, has been using microscope-integrated intraoperative OCT for the past year. In their white paper “Intraoperative Optical Coherence Tomography:…