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Science Lab

Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
Caption: Collaboration is key Picture copyright: Donenko Oleksii, Shutterstock

Launching a Neurosurgical Department with Limited Resources

Learn about Dr. Claire Karekezi’s journey and experience launching a neurosurgical department within the Rwanda Military Hospital with limited resources.
Application example of hyperspectral imaging

Expanding The Frontiers of Multiplex Imaging

Join us for this webinar & explore the new frontiers of multi-color fluorescent imaging: from image acquisition to analysis
Brain organoid section (DAPI) acquired using THUNDER Imager Live Cell. Image courtesy of Janina Kaspar and Irene Santisteban, Schäfer Lab, TUM.

Imaging Organoid Models to Investigate Brain Health

Imaging human brain organoid models to study the phenotypes of specialized brain cells called microglia, and the potential applications of these organoid models in health and disease.

Mastering Multiplex Immunofluorescence: Techniques and Troubleshooting

This webinar combines the expertise to provide a comprehensive overview of multiplex immunofluorescence staining and imaging with practical tips.
In vivo imaging of a mouse pial and cortical vasculature through a glass window (ROSAmT/mG::Pdgfb-CreERT2 mouse meningeal and cortical visualization following tamoxifen induction and craniotomy). Courtesy: Thomas Mathivet, PhD

Windows on Neurovascular Pathologies

Discover how innate immunity can sustain deleterious effects following neurovascular pathologies and the technological developments enabling longitudinal studies into these events.
Lifetime-based multiplexing in live cells using TauSeparation. Mammalian cells expressing LifeAct-GFP (ibidi GmbH) and labelled with MitoTracker Green. Acquisition with one detector, intensity information shown in grey. The two markers can be separated using lifetime information: LifeAct-GFP (cyan), MitoTracker Green (magenta). Image acquired with STELLARIS 5.

The Power of Reproducibility, Collaboration and New Imaging Technologies

In this webinar you willl learn what impacts reproducibility in microscopy, what resources and initiatives there are to improve education and rigor and reproducibility in microscopy and how…
Advanced technologies support neurosurgical teaching. Image courtesy of Dr. Florian Bernard.

3D, AR & VR for Teaching in Neurosurgery

Discover the evolution of neurosurgical teaching and how 3D, Augmented Reality and Virtual Reality can help better learn anatomy and acquire surgical skills.
THY1-EGFP labeled neurons in mouse brain processed using the PEGASOS 2 tissue clearing method, imaged on a Leica confocal microscope. Neurons were traced using Aivia’s 3D Neuron Analysis – FL recipe. Image credit: Hu Zhao, Chinese Institute for Brain Research.

Unlocking Insights in Complex and Dense Neuron Images Guided by AI

The latest advancement in Aivia AI image analysis software provides improved soma detection, additional flexibility in neuron tracing, 3D relational measurement including Sholl analysis and more.

How to Prepare and Analyse Battery Samples with Electron Microscopy

This online workshop is designed for beginners as well as advanced EM users for lithium or novel battery systems, as well as other semiconductor samples requiring high-resolution cross-section…
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