Science Lab

We expand upon our recent, fundamental report on solvent immersion imprint lithography (SIIL) and describe a semi-automated and high-performance…

Biological rhythms controlled by the circadian clock are absent in embryonic stem cells (ESCs). However, they start to develop during the…

Pathologic electrical remodeling and attenuated cardiac contractility are featured characteristics of heart failure. Coinciding with these remodeling…

Alpha-synuclein (α-Syn) aggregation into oligomers and fibrils is associated with dopaminergic neuron loss occurring in Parkinson’s disease (PD)…

Heparan Sulfate Proteoglycans act as a cell surface co-receptors for many proteins in which a signal is sent downstream via its cytosolic domain. The…

Heavy metal contamination in water is a serious risk to the public health and other life forms on earth. Current research in nanotechnology is…

This article published in the journal OSLI Retina discusses the findings of the latest phase of the DISCOVER study relating specifically to the…

Jennifer Doudna tells the story of how studying the way bacteria fight viral infection turned into a genomic engineering technology that has…

This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including…

In vascular and neoplastic surgery sylvian dissection is an essential skill. The neurosurgeon needs to recognize the superficial sylvian vein (SSV) in…

Francisco Mojica was not the first to see CRISPR, but he was probably the first to be smitten by it. He remembers the day in 1992 when he got his…

While distinct stages of natural killer (NK) cell development have been defined, the molecular interactions that shape human NK cell maturation are…

Long distance transport in plants occurs in sieve tubes of the phloem. The pressure flow hypothesis introduced by Ernst Münch in 1930 describes a…

Human peripheral blood contains RNA in cells and in extracellular membrane vesicles, microvesicles and exosomes, as well as in cell-free…

Plasma membrane dynamics are an important ruler of cellular activity, particularly through the interaction and diffusion dynamics of membrane-embedded…

Correlative light and electron microscopy is an imaging technique that enables identification and targeting of fluorescently tagged structures with…

Application example for laser microdissection (LMD) - MicroRNAs (miRNAs) play important roles in regulating biological processes at the…

Using Arabidopsis (Arabidopsis thaliana) seedlings, we identified a range of small fluorescent probes that entered the translocation stream and were…