Science Lab
Science Lab
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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How to Prepare your Specimen for Immunofluorescence Microscopy
Immunofluorescence (IF) is a powerful method for visualizing intracellular processes, conditions and structures. IF preparations can be analyzed by various microscopy techniques (e.g. CLSM,…
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Live-Cell Imaging Techniques
The understanding of complex and/or fast cellular dynamics is an important step for exploring biological processes. Therefore, today’s life science research is increasingly focused on dynamic…
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Fluorescent Dyes
A basic principle in fluorescence microscopy is the highly specific visualization of cellular components with the help of a fluorescent agent. This can be a fluorescent protein – for example GFP –…
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Using Machine Learning in Microscopy Image Analysis
Recent exciting advances in microscopy technologies have led to exponential growth in quality and quantity of image data captured in biomedical research. However, analyzing large and increasingly…
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The AI-Powered Pixel Classifier
Achieving reproducible results manually requires expertise and is tedious work. But now there is a way to overcome these challenges by speeding up this analysis to extract the real value of the image…
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Multicolor Microscopy: The Importance of Multiplexing
The term multiplexing refers to the use of multiple fluorescent dyes to examine various elements within a sample. Multiplexing allows related components and processes to be observed in parallel,…
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How to Select a Microscope for Cataract Surgery
What to consider in the selection of an ophthalmic microscope for cataract procedures. Bearing these aspects in mind will equip surgeons well for talks with manufacturer representatives. Many…
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Save Time and Effort with AI-assisted Fluorescence Image Analysis
The powerful synergy of THUNDER and Aivia analyze fluorescence images with greater accuracy, even when using low light excitation.
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How to Select the Right Solution for Visual Inspection
This article helps users with the decision-making process when selecting a microscope as a solution for routine visual inspection. Important factors that should be considered are described.