Science Lab

Science Lab


Latest Articles
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Interview with Stefan Hell – For me, Pioneering is …
Our interview partner on the topic of Pioneering is Prf. Stefan Hell, a scientific member of the Max Planck Society and director at the Max Planck…
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The First Supercontinuum Confocal that Adapts to the Sample
Until now, biological and medical research fluorescence imaging in multi-user facilities or institutes has been limited by the type or number of dyes…
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From Molecules to Tissues
Cancer research using confocal and multiphoton microscopy. Sequencing of the human genome stimulated a radical change in the approach to biomedical…
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Obese and Slim Yeast Cells
Lipids are on everyone’s lips nowadays, whether ω-3/6 fatty acids, good and bad cholesterol or just plain fat that has the annoying habit of…
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The Future of Forensic Training Programs
Wayne Buttermore, Manager Regional Sales Industry at Leica Microsystems, interviewed Skip Palenik to hear his perspective on the benefits of…
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Forensic Detection of Sperm from Sexual Assault Evidence
The impact of modern scientific methods on the analysis of crime scene evidence has dramatically changed many forensic sub-specialties. Arguably one…
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Beware of "Empty" Magnification
This article explains how to avoid the phenomen of "empty magnification" in microscopy.
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Quality as Clear as Glass - Polarizing Microscopy in Glass Production
An exquisite beverage deserves a high-quality glass. Even the ancient Romans made artistically crafted drinking glasses. In the Middle Ages, Venetian…
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FusionOptics – Combines high resolution and depth of field for ideal 3D optical Images
A study carried out jointly by Leica Microsystems and the Institute of Neuroinformatics at the University of Zurich and Swiss Federal Institute of…
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Implementing Ergonomic Design for Microscope Workstations
This study evaluated the effect of an occupational therapy ergonomics intervention on the workstation design and body positioning of microscope…
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Exploring Cell Logistics
Using TIRF microscopy, scientists have been able to take a closer look at intracellular transport processes with the example of the galactose-binding…
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In the Footsteps of Linnaeus – Microscopic Imaging in Marine Biodiversity Research
For the study of minute marine organisms such as free swimming larvae or bottom dwelling invertebrates it is a great advantage to have modern…
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Characterization of Photosynthetic Biofilms from Roman Catacombs via 3D Imaging and Subcellular Identification of Pigments
Artificial illumination can harm hypogean monuments by inducing the uncontrolled growth of photosynthetic biofilms (green sickness or maladie verte).…
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CLEM: Combining the Strengths of Light and Electron Microscopy
In recent years light microscopy studies have been dominated by live cell imaging while electron microscopy has been used for high-resolution studies.…
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The History of Stereo Microscopy – Part III
Until the middle of the 19th century, microscopes were hand-crafted custom instruments. At the time, it was not possible to predict the properties of…
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The History of Stereo Microscopy – Part II
For millennia, glass was admired for its beauty and the artful objects that could be created with it. With the rise of the exact sciences, however,…
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The History of Stereo Microscopy – Part I
The 17th century in Europe was marked by the Thirty Years' War (1618–1648). The population lived in constant fear and poverty. Marauding hordes…
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4D Photoactivation of pa-GFP in Living Cells Using Two-Photon Excitation Laser Scanning Microscopy
We report about two-photon activation of a photoactivatable derivative of the Aequorea Victoria green fluorescent protein (pa-GFP). This special form…

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