Science Lab

Science Lab

The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!

Latest Articles

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Investigating Pulmonary Vascular Diseases
This article describes how the cellular and molecular programs governing the formation and maintenance of lung blood vessels, as well as what goes…
Mar 03, 2022
Case Study
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How to Benefit from Digital Cytopathology
If you have thought of digital cytopathology as characterized by the digitization of glass slides, this webinar with Dr. Alessandro Caputo from the…
Mar 02, 2022
Webinar
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Deciphering Signaling Pathways in Developmental Biology
This article shows how sharp, rapid imaging of neuronal progenitors in chick embryos with a THUNDER Imager Model Organism and small volume…
Feb 24, 2022
Case Study
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Verifying Specifications for Auto Parts and Components
During the development and production of automotive parts and components, whether by suppliers or the auto manufacturer, specifications must be met.…
Feb 23, 2022
Whitepaper
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Multicellular Organization during Stem Cell Dynamics
Multicellular organization, e.g. during tissue morphogenesis or of human embryonic stem cells, relies on collective cytoskeletal dynamics. During…
Feb 21, 2022
Abstract
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Phosphoprotein Regulates Integrin Endosomal Trafficking
Integrins are involved in cell-cell and cell-extracellular matrix adhesion. In addition, they mediate several signaling pathways, regulating e.g. cell…
Feb 21, 2022
Abstract
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Structural HIV-1 Env Trimers Dynamics on Living T Cells
In this article, we focus on the molecular mechanism of the Env protein as it interacts with T cell, the primary target of HIV-1 [Carlon-Andres I et…
Feb 09, 2022
Abstract
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Cataract Surgery Symposium Replay
It is estimated that nearly 28 million cataract surgery procedures are performed worldwide every year. Phacoemulsification is the most common method…
Feb 09, 2022
Webinar
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Factors for Selecting Clinical Microscopes
If you are considering the purchase of new clinical microscopes for yourself or your team, you will think about many options, vendors, and microscope…
Feb 02, 2022
Story
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Clinical Microscopy: Considerations on Camera Selection
The need for images in pathology laboratories has significantly increased over the past few years, be it in histopathology, cytology, hematology,…
Feb 02, 2022
Story
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Visualizing retinal interactions to study eye diseases
This article shows how interactions between endothelial cells, blood vessels, microglia, and astrocytes in mouse retina can be studied efficiently…
Jan 28, 2022
Case Study
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Free Flap Procedures in Oncological Reconstructive Surgery
Free flap surgery is considered the gold standard for breast, head and neck reconstructions for cancer patients. These procedures, which enable…
Jan 27, 2022
Story
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Minor’s Disease Surgical Intervention
Minor’s disease, also called Superior Semicircular Canal Dehiscence (SSCD) or Minor’s syndrome, is a rare disorder of the inner ear that affects…
Jan 27, 2022
Case Study
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How to Choose a Microscope for Reconstructive Surgery
Plastic and reconstructive surgery requires excellent visualization to repair intricate and fine structures. Oncological reconstructive surgery…
Jan 27, 2022
Story
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Cranial Nerve Development
This article demonstrates how fast, high-contrast imaging of mouse embryos with a THUNDER Imager 3D Cell Culture and Large Volume Computational…
Jan 27, 2022
Case Study
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Advances in Oncological Reconstructive Surgery
Decision making and patient care in oncological reconstructive surgery have considerably evolved in recent years. New surgical assistance technologies…
Jan 27, 2022
Whitepaper
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The Time to Diagnosis is Crucial in Clinical Pathology
Abnormalities in tissues and fluids - that’s what pathologists are looking for when they examine specimens under the microscope. What they see and…
Jan 26, 2022
Interview
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A Versatile Palette of Fluorescent Probes
Researchers at the Max Planck Institute for Medical Research in Heidelberg have developed a general strategy to synthesize live-cell compatible…
Jan 24, 2022
Abstract