The Microscopy Knowledge Portal
The knowledge portal of Leica Microsystems offers scientific research and teaching material on the subjects of microscopy. The content is designed to support beginners, experienced practitioners and scientists alike in their everyday work and experiments. Explore interactive tutorials and application notes, discover the basics of microscopy as well as high-end technologies – become part of the Science Lab community and share your expertise!
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Topics – A Vast Amount of Expert Knowledge
- Basics in Microscopy
- Confocal Microscopy
- Digital Microscopy
- Dentistry
- EM Sample Preparation
- Fluorescence Microscopy
- Light Sheet Microscopy
- Neurosurgery
- Optical Coherence Tomography
- Super-Resolution
- Stereo Microscopy
- Surface Metrology
- Quality Assurance
- Otolaryngology (ENT)
- Ophthalmology
- Plastic Reconstructive
- Widefield Microscopy
- More
Latest Articles
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Improved Visualization of the Anterior Chamber Angle with Proveo 8
In this interview, Michael G. Richie, MD offers his expert opinion on the Proveo 8 from Leica Microsystems as a means for outstanding visualization of…
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Intraoperative OCT as a Tool to Treat Diabetic Patients
In this interview, Asheesh Tewari, MD, details his experience with Proveo 8 with EnFocus Intraoperative OCT from Leica Microsystems. He finds it a…
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Spectroscopic Evaluation of Red Blood Cells
Hemoglobinopathies are a major healthcare problem. This study presents a possible diagnostic tool for thalassemia which is based on confocal…
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How to use a Surgical Microscope as an Operating Room Nurse
Surgical microscopes play an essential role in the modern microsurgery procedures. It provides the surgeon, assistant and operating room staff with a…
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How to Improve Live Cell Imaging with Leica Nano Workflow
For live-cell CLEM applications, light microscopy imaging is a critical step for identifying the right cell in the right state at the right time. In…
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Effects of Clearing Media on Tissue Transparency and Shrinkage
This study comprehensively evaluates the effects of different clearing media on tissue transparency and shrinkage by comparing freshly dissected…
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Cortical Contributions to Complex Learning
This article describes the use of sharp, high contrast imaging to facilitate assessment of viral-construct placement in rat cortical brain tissue.…
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Download TauSTED Infographic
TauSTED combines the optical signals from STED and the physical information from fluorescence lifetime at confocal speeds. Outstanding STED resolution…
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Visualization of Submitochondrial Protein Distributions
By allowing visualization of submitochondrial protein distributions, fluorescence nanoscopy offers significant advantages for understanding cell death…
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The Cryo-CLEM Journey
This article describes the Cryo-CLEM technology and the benefits it can provide for scientists. Additionally, some scientific publications are…
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DNA Replication in Cancer Cells
DNA synthesis can be impeded by collisions between the DNA replication machinery and co-transcriptional R-loops leading to a major source of genomic…
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Clinical Symposium on OCT-guided Cornea Surgery
In this recording Prof. Mehta from Singapore National Eye Centre and Prof. Fontana from Santa Maria Nuova Hospital in Regio Emilia, Italy, share…
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How to Keep Your Samples Under Physiological Conditions
Leica Microsystems’ Nano workflow combines dynamic data with the best possible sample fixation (EM ICE 70) by high pressure freezing. However, good…
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Fluorescence Lifetime-based Imaging Gallery
Confocal microscopy relies on the effective excitation of fluorescence probes and the efficient collection of photons emitted from the fluorescence…
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Optimizing THUNDER Platform for High-Content Slide Scanning
With rising demand for full-tissue imaging and the need for FL signal quantitation in diverse biological specimens, the limits on HC imaging…
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Visualizing Protein Degradation and Aggregation in the Living Cell
Our guest speaker, Prof Dr Eric Reits, presents his work on neurodegenerative disorders. Reits’ group are experts on the subject of Huntington’s…
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Towards Advanced Use of Intraoperative OCT in Cataract Surgery
In this White Paper, Dr. Rachid Tahiri shares his personal experience with the Leica EnFocus intraoperative OCT, the valuable features supporting…
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How Clinical and Surgical Microscopes Support Otolaryngology
The number of ENT surgery procedures is increasing year after year. It is estimated that there will be over 21 million ENT procedures performed…
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Topics
- All
- Live-Cell Imaging
- Light Sheet Microscopy
- Super-Resolution
- Widefield Microscopy
- THUNDER Imaging
- Fluorescence Microscopy
- Optical Coherence Tomography
- Surgical Microscopy
- Confocal Microscopy
- Laser Microdissection
- Neuroscience
- Forensics
- Quality Assurance
- Stereo Microscopy
- Digital Microscopy
- Ophthalmology
- Multiphoton Microscopy
- Quantitative Imaging
- Coherent Raman Scattering (CRS)
- CLEM
- EM Sample Preparation
- Neurosurgery
- Education
- Otolaryngology (ENT)
- Plastic Reconstructive
- TIRF Microscopy
- Surface Metrology
- Metallography
- Basics in Microscopy
- Steel Quality
- Dentistry
- CRISPR-Cas9
- Conservation
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